-
Chapter and Conference Paper
Uncertainty Estimation and Propagation in Accelerated MRI Reconstruction
MRI reconstruction techniques based on deep learning have led to unprecedented reconstruction quality especially in highly accelerated settings. However, deep learning techniques are also known to fail unexpec...
-
Article
Open AccessAmending China’s Notion of a “Consumer”: Lessons from Comparative Analysis of the PRC Consumer Protection Law
Who does the law treat as a “consumer” and why does it matter? How should China’s notion of a “consumer” best be articulated within the law and applied in practice? This article will attempt to answer these in...
-
Article
Open AccessRandomised controlled trial of oxygen therapy and high-flow nasal therapy in African children with pneumonia
The life-saving role of oxygen therapy in African children with severe pneumonia is not yet established.
-
Chapter and Conference Paper
Determination of a Dedicated, Cost-Effective Agility in Manufacturing Networks
Global manufacturing companies are operating their manufacturing networks in an increasingly uncertain and complex environment. Consequently, they have to adapt their networks much faster to changing condition...
-
Chapter and Conference Paper
Combining Process Mining and Machine Learning for Lead Time Prediction in High Variance Processes
Machine learning offers a high potential for the prediction of manufacturing lead times. In practical operations the lack of defined processes and high-quality input data are a major obstacle for the use of ma...
-
Chapter and Conference Paper
Systematization of Adaptation Needs in the Design of Global Production Networks
In order to ensure long-term competitiveness, production networks need to be designed in a continuous way that allows a quick adaptation to changing conditions. Today, due to high complexity in production netw...
-
Article
Open AccessTreatment modalities and drug survival in a systemic sclerosis real-life patient cohort
European data indicate that systemic sclerosis (SSc)-related death rates are increasing, thus raising concerns about SSc’s optimal management. Herein, we describe current treatment modalities and drug survival...
-
Article
Open AccessHigher body mass index is linked to altered hypothalamic microstructure
Animal studies suggest that obesity-related diets induce structural changes in the hypothalamus, a key brain area involved in energy homeostasis. Whether this translates to humans is however largely unknown. U...
-
Article
Elevated and cryogenic temperature micropillar compression of magnesium–niobium multilayer films
The mechanical properties of multilayer films consisting of alternating layers of magnesium and niobium are investigated through micropillar compression experiments across a broad range of temperatures. The da...
-
Article
Open AccessAggressive fibromatosis response to tamoxifen: lack of correlation between MRI and symptomatic response
One of the commonly used systemic agents for the treatment of aggressive fibromatosis is the anti-oestrogen drug tamoxifen. However, data on efficacy and optimum methods of response assessment are limited, con...
-
Article
Open AccessESICM LIVES 2016: part two
-
Article
Management of orthodontic emergencies in primary care – self-reported confidence of general dental practitioners
Highlights that orthodontic emergencies do not frequently present to general dental practitioners.
Outlines...
-
Article
Open AccessNew insights into the pharmacokinetics and pharmacodynamics of natalizumab treatment for patients with multiple sclerosis, obtained from clinical and in vitro studies
The monoclonal antibody natalizumab (NAT) inhibits the migration of lymphocytes throughout the blood–brain barrier by blocking very late antigen (VLA)-4 interactions, thereby reducing inflammatory central nerv...
-
Article
Open AccessPhase I trial outcomes in older patients with advanced solid tumours
This study had two aims: (a) to test the hypothesis that advanced age is associated with lower levels of tolerability and clinical benefit to experimental Phase I trial agents; (b) to assess the validity of th...
-
Article
Evaluation of soil erosion risk for watershed management in Shenmu watershed, central Taiwan using USLE model parameters
This study compiles the latest regional topographic data from field investigation and remote-sensing images to recalculate parameters of the universal soil loss equation (USLE) model of the Shenmu watershed; a...
-
Article
Erectile dysfunction after radiotherapy for prostate cancer: a model assesing the conflicting literature on dose–volume effects
Studies assessing the relationship between dose to the penile bulb (PB) and risk of ED in men treated for prostate cancer with external beam radiation therapy (EBRT) have been critically scored. A review of pu...
-
Article
Open AccessAssessment of the dynamic range in dynamic contrast-enhanced magnetic resonance imaging breast examinations
-
Article
Open AccessA phase I/II trial of sorafenib and infliximab in advanced renal cell carcinoma
BACKGROUND: There is clinical evidence to suggest that tumour necrosis factor-α (TNF-α) may be a therapeutic target in renal cell carcinoma (RCC). Multi-targeted kinase inhibitors, such as sorafenib and sunitinib...
-
Article
Laparoscopic caecodivision ACE (antegrade continence enema) procedure
Since the first description of the antegrade colonic enema (ACE) procedure by Malone in 1990 [1], multiple modifications have been developed to overcome some of the initial problems. We describe what we believ...
-
Article
Partial and whole gene deletion mutations of the GCK and HNF1A genes in maturity-onset diabetes of the young
Heterozygous mutations of glucokinase (GCK) and hepatocyte nuclear factor-1 alpha (HNF1A; also known as hepatic transcription factor 1 [TCF1]) genes are the most common cause of MODY. Genomic deletions of the HNF...
