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  1. No Access

    Article

    Wegener’s granulomatosis in the thyroid mimicking a tumour

    Wegener’s granulomatosis (WG) is a systemic vasculitis characterised by the presence of necrotizing granulomas and classically manifests as a triad of upper and lower respiratory tract involvement along with g...

    K. J. Schmitz, M. W. Baumgaertel, C. Schmidt, S. Y. Sheu, M. Betzler… in Virchows Archiv (2008)

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    Article

    Activation of extracellular regulated kinases (ERK1/2) but not AKT predicts poor prognosis in colorectal carcinoma and is associated with k-ras mutations

    Signal transduction and modulation represent central mechanisms in cellular processes such as cell-cycle regulation, oncogenesis, and apoptosis. The aim of this study was to determine the prognostic relevance ...

    K. J. Schmitz, J. Wohlschlaeger, H. Alakus, J. Bohr, M. A. Stauder… in Virchows Archiv (2007)

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    Article

    Relationship and prognostic significance of phospho-(serine 166)-murine double minute 2 and Akt activation in node-negative breast cancer with regard to p53 expression

    The Akt signalling pathway plays a central role in tumourigenesis. Activation of Akt is related to a more aggressive phenotype in various human cancers, including breast cancer. Its activation contributes to c...

    K. J. Schmitz, F. Grabellus, R. Callies, J. Wohlschlaeger, F. Otterbach… in Virchows Archiv (2006)

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    Chapter

    Contamination of ground-water by cyanide-bearing former refuse deposits — a case study

    Since 1982 some flat wells for drinking and industrial water supply — situated in the Lower Terrace aquifier of the Rhine river — show contamination by cyanids.

    K. J. Schmitz, Dr. Hubertus Mertes in Contaminated Soil ’88 (1988)