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    Generation, selection and preclinical characterization of an Fc-optimized FLT3 antibody for the treatment of myeloid leukemia

    The therapeutic efficacy of humanized or chimeric second-generation antitumor antibodies is clearly established, but often limited. In recent years, defined modifications of the glycosylation pattern or the am...

    M Hofmann, L Große-Hovest, T Nübling, E Pyż, M L Bamberg, S Aulwurm… in Leukemia (2012)