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  1. No Access

    Article

    The pathogenesis of mucositis: updated perspectives and emerging targets

    Mucositis research and treatment are a rapidly evolving field providing constant new avenues of research and potential therapies. The MASCC/ISOO Mucositis Study Group regularly assesses available literature re...

    J. Bowen, N. Al-Dasooqi, P. Bossi, H. Wardill, Y. Van Sebille… in Supportive Care in Cancer (2019)

  2. No Access

    Article

    Tumor-secreted anterior gradient-2 binds to VEGF and FGF2 and enhances their activities by promoting their homodimerization

    The importance of the tumor microenvironment in targeted anticancer therapies has been well recognized. Various protein factors participate in the cross-talk between tumor cells and non-malignant cells. Anteri...

    H Guo, Q Zhu, X Yu, S B Merugu, H B Mangukiya, N Smith, Z Li, B Zhang, H Negi… in Oncogene (2017)

  3. No Access

    Article

    A new pathway for the gut microbiota to modulate the brain: activation of pattern-recognition receptors by microbial products

    P Zheng, K Cheng, L Zeng, C-J Zhou, P **e in Molecular Psychiatry (2017)

  4. No Access

    Article

    Cortical bone laminar analysis reveals increased midcortical and periosteal porosity in type 2 diabetic postmenopausal women with history of fragility fractures compared to fracture-free diabetics

    We investigated the characteristics and spatial distribution of cortical bone pores in postmenopausal women with type 2 diabetes (T2D). High porosity in the midcortical and periosteal layers in T2D subjects wi...

    U. Heilmeier, K. Cheng, C. Pasco, R. Parrish, J. Nirody… in Osteoporosis International (2016)

  5. No Access

    Article

    Cables1 controls p21/Cip1 protein stability by antagonizing proteasome subunit alpha type 3

    The cyclin-dependent kinase (CDK) inhibitor 1A, p21/Cip1, is a vital cell cycle regulator, dysregulation of which has been associated with a large number of human malignancies. One critical mechanism that cont...

    Z Shi, Z Li, Z J Li, K Cheng, Y Du, H Fu, F R Khuri in Oncogene (2015)

  6. Article

    Synergistic effects of genetic beta cell dysfunction and maternal glucose intolerance on offspring metabolic phenotype in mice

    Diabetes in pregnancy is linked to development of obesity in the offspring, but the mechanisms are not fully understood. Gestational diabetes mellitus (GDM) occurs when beta cells are unable to compensate for ...

    S. M. Lau, S. Lin, R. A. Stokes, K. Cheng, P. A. Baldock, R. F. Enriquez… in Diabetologia (2011)

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  7. No Access

    Article

    The leukemia-associated cytoplasmic nucleophosmin mutant is an oncogene with paradoxical functions: Arf inactivation and induction of cellular senescence

    Mutations leading to aberrant cytoplasmic localization of Nucleophosmin 1 (NPM1) have been recently identified as the most frequent genetic alteration in acute myelogenous leukemia. However, the oncogenic potenti...

    K Cheng, S Grisendi, J G Clohessy, S Majid, R Bernardi, P Sportoletti… in Oncogene (2007)

  8. Article

    40th EASD Annual Meeting of the European Association for the Study of Diabetes

    M. Veitenhansl, K. Stegner, F.-X. Hierl, C. Dieterle, H. Feldmeier, B. Gutt… in Diabetologia (2004)

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  9. No Access

    Article

    Autoantibodies to Abl and Bcr proteins

    Formation of an aberrant, chimeric Bcr-Abl protein is the hallmark of Philadelphia (Ph) chromosome-positive leukemias. The Bcr-Abl protein, as well as its normal cellular counterparts – Abl and Bcr – are intra...

    M Talpaz, X Qiu, K Cheng, JE Cortes, H Kantarjian, R Kurzrock in Leukemia (2000)

  10. No Access

    Chapter

    A Weak Substance P Antagonist Inhibits L-692,585-Stimulated GH Release in Swine

    Growth hormone (GH) releasing hexapeptide, His-DTrp-Ala-Trp-DPhe- LysNH2 (GHRP-6), was first described as a potent GH-specific secretagogue by Bowers, et al. (2). The first described nonpeptidyl GH secretagogu...

    C. Chang, E. Rickes, L. McGuire, S. Cosgrove, E. Frazier… in Growth Hormone Secretagogues (1996)