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    Article

    Extranodal connective tissue invasion and the expression of desmosomal glycoprotein 1 in squamous cell carcinoma of the oesophagus

    We investigated extranodal connective tissue involvement (ECTI) in 39 patients with oesophageal carcinoma. Both the primary tumour and ECTI were immunohistochemically examined using the monoclonal antibody 32-...

    S Natsugoe, J Mueller, F Kijima, K Aridome, M Shimada in British Journal of Cancer (1997)

  2. No Access

    Article

    Truncated midkine as a marker of diagnosis and detection of nodal metastases in gastrointestinal carcinomas

    Midkine (MK) is a growth factor identified as a product of a retinoic acid-responsive gene. A truncated form of MK mRNA, which lacks a sequence encoding the N-terminally located domain, was recently found in c...

    K Aridome, S Takao, T Kaname, K Kadomatsu, S Natsugoe in British Journal of Cancer (1998)

  3. Article

    Open Access

    Serum midkine levels are increased in patients with various types of carcinomas

    The level of expression of midkine (MK), a heparin-binding growth factor, is increased in many types of human carcinomas. An enzyme-linked immunoassay, which utilizes a combination of rabbit and chicken antibo...

    S Ikematsu, A Yano, K Aridome, M Kikuchi, H Kumai, H Nagano in British Journal of Cancer (2000)

  4. Article

    Open Access

    Clinical significance of midkine expression in pancreatic head carcinoma

    Midkine (MK) is a heparin-binding growth factor and a product of a retinoic acid-responsive gene. Midkine is overexpressed in many carcinomas and thought to play an important role in carcinogenesis. However, n...

    S Maeda, H Shinchi, H Kurahara, Y Mataki, H Noma, K Maemura in British Journal of Cancer (2007)