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Sox9 Potentiates BMP2-Induced Chondrogenic Differentiation and Inhibits BMP2-Induced Osteogenic Differentiation

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  1. Article

    Open Access

    Prevalence and associations of sarcopenia, obesity and sarcopenic obesity in end-stage knee osteoarthritis patients

    To identify the prevalence of obesity, sarcopenia, sarcopenic obesity in end-stage knee osteoarthritis (KOA) patients and analyze influences of obesity and sarcopenia in the progression of KOA.

    Junyi Liao, Jie Chen, Wei Xu, Jia Chen in Journal of Health, Population and Nutrition (2023)

  2. Article

    Open Access

    The natural product salicin alleviates osteoarthritis progression by binding to IRE1α and inhibiting endoplasmic reticulum stress through the IRE1α-IκBα-p65 signaling pathway

    Despite the high prevalence of osteoarthritis (OA) in older populations, disease-modifying OA drugs (DMOADs) are still lacking. This study was performed to investigate the effects and mechanisms of the small m...

    Zhenglin Zhu, Shengqiang Gao, Cheng Chen, Wei Xu in Experimental & Molecular Medicine (2022)

  3. Article

    Open Access

    Retraction Note to: Schnurri-3 regulates BMP9-induced osteogenic differentiation and angiogenesis of human amniotic mesenchymal stem cells through Runx2 and VEGF

    Yuwan Li, Ziming Liu, Ya** Tang, Wei Feng, Chen Zhao, Junyi Liao in Cell Death & Disease (2021)

  4. Article

    Open Access

    Silencing Smad7 potentiates BMP2-induced chondrogenic differentiation and inhibits endochondral ossification in human synovial-derived mesenchymal stromal cells

    Bone morphogenetic protein 2 (BMP2) is a promising chondrogenic growth factor for cartilage tissue-engineering, but it also induces robust endochondral ossification. Human synovial-derived mesenchymal stromal ...

    Pengcheng **ao, Zhenglin Zhu, Chengcheng Du, Yongsheng Zeng in Stem Cell Research & Therapy (2021)

  5. Article

    Open Access

    RETRACTED ARTICLE: Schnurri-3 regulates BMP9-induced osteogenic differentiation and angiogenesis of human amniotic mesenchymal stem cells through Runx2 and VEGF

    Human amniotic mesenchymal stem cells (hAMSCs) are multiple potent progenitor cells (MPCs) that can differentiate into different lineages (osteogenic, chondrogenic, and adipogenic cells) and have a favorable c...

    Yuwan Li, Ziming Liu, Ya** Tang, Wei Feng, Chen Zhao, Junyi Liao in Cell Death & Disease (2020)

  6. Chapter

    Correction to: Sox9 Potentiates BMP2-Induced Chondrogenic Differentiation and Inhibits BMP2-Induced Osteogenic Differentiation

    Correction to: D. Duscher, M. A. Shiffman (eds.), Regenerative Medicine and Plastic Surgery: Skin and Soft Tissue, Bone, Cartilage, Muscle, Tendon and Nerves, at https://doi.org/10.1007/978-3-030-199...

    Junyi Liao, Ning Hu, Nian Zhou, Chen Zhao in Regenerative Medicine and Plastic Surgery (2019)

  7. Article

    Open Access

    An effective treatment of experimental osteomyelitis using the antimicrobial titanium/silver-containing nHP66 (nano-hydroxyapatite/polyamide-66) nanoscaffold biomaterials

    Effective treatment of osteomyelitis remains a formidable clinical challenge. The rapid emergence of multidrug-resistant bacteria has renewed interest in develo** antimicrobial biomaterials using antiseptic ...

    Minpeng Lu, Junyi Liao, **g Dong, Jun Wu, Hao Qiu, **n Zhou in Scientific Reports (2016)

  8. Article

    Open Access

    Antibiotic monensin synergizes with EGFR inhibitors and oxaliplatin to suppress the proliferation of human ovarian cancer cells

    Ovarian cancer is the most lethal gynecologic malignancy with an overall cure rate of merely 30%. Most patients experience recurrence within 12–24 months of cure and die of progressively chemotherapy-resistant...

    Youlin Deng, Junhui Zhang, Zhongliang Wang, Zhengjian Yan, Min Qiao in Scientific Reports (2015)