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Open AccessHigh levels of high-density lipoprotein cholesterol may increase the risk of diabetic kidney disease in patients with type 2 diabetes
Studies have indicated that low high-density lipoprotein cholesterol (HDL-C) level is an important risk factor for diabetic kidney disease (DKD) in patients with type 2 diabetes (T2D). However, whether higher ...
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Open AccessInvestigation on the control of inclusions and tensile strength in Ce-treated P110-grade oil casing steel
This research added rare Earth elements Ce to the P110-grade oil casing steel to reveal their influence on the inclusions and tensile properties. The content of cerium in the steel varied from 0 to 452 ppm. Ba...
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Open AccessAuthor Correction: High-power electrically pumped terahertz topological laser based on a surface metallic Dirac-vortex cavity
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Open AccessHigh-power electrically pumped terahertz topological laser based on a surface metallic Dirac-vortex cavity
Topological lasers (TLs) have attracted widespread attention due to their mode robustness against perturbations or defects. Among them, electrically pumped TLs have gained extensive research interest due to th...
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Open AccessA fungal core effector exploits the OsPUX8B.2–OsCDC48-6 module to suppress plant immunity
Proteins containing a ubiquitin regulatory X (UBX) domain are cofactors of Cell Division Cycle 48 (CDC48) and function in protein quality control. However, whether and how UBX-containing proteins participate i...
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Water-responsive supercontractile polymer films for bioelectronic interfaces
Connecting different electronic devices is usually straightforward because they have paired, standardized interfaces, in which the shapes and sizes match each other perfectly. Tissue–electronics interfaces, ho...
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Open AccessZSP1601, a novel pan-phosphodiesterase inhibitor for the treatment of NAFLD, A randomized, placebo-controlled phase Ib/IIa trial
Non-alcoholic fatty liver disease is a growing health burden with limited treatment options worldwide. Herein we report a randomized, double-blind, placebo-controlled, multiple-dose trial of a first-in-class p...
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Open AccessIn-situ electro-responsive through-space coupling enabling foldamers as volatile memory elements
Voltage-gated processing units are fundamental components for non-von Neumann architectures like memristor and electric synapses, on which nanoscale molecular electronics have possessed great potentials. Here,...
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Open AccessStability analysis and control technology of the sump-surrounding rock under a 1200-m-deep goaf: a case study
In this study, a sump in the **ngdong coal mine (buried at a depth of over 1200 m) was used to analyze the surrounding rock's stability and control technology. Under the combined influences of various complex ...
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Open AccessAuthor Correction: Toward the design of ultrahigh-entropy alloys via mining six million texts
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Open AccessThe NuRD complex cooperates with SALL4 to orchestrate reprogramming
Cell fate decision involves rewiring of the genome, but remains poorly understood at the chromatin level. Here, we report that chromatin remodeling complex NuRD participates in closing open chromatin in the ea...
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Open AccessInfluence of the ultra-fine fly ash dosages on the mechanical properties of the sulfoaluminate cement-based high water backfilling material
To reduce the filling cost of high-water backfilling material (HWBM) in mining backfill and improve the recycling utilization of the industrial waste such as the coal fly ash. The ultra-fine fly ash (UFA) was ...
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Open AccessVolumetric additive manufacturing of pristine silk-based (bio)inks
Volumetric additive manufacturing (VAM) enables fast photopolymerization of three-dimensional constructs by illuminating dynamically evolving light patterns in the entire build volume. However, the lack of bio...
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Open AccessToward the design of ultrahigh-entropy alloys via mining six million texts
It has long been a norm that researchers extract knowledge from literature to design materials. However, the avalanche of publications makes the norm challenging to follow. Text mining (TM) is efficient in ext...
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Open AccessPrebiopsy bpMRI and hematological parameter-based risk scoring model for predicting outcomes in biopsy-naive men with PSA 4–20 ng/mL
Excessive prostate biopsy is a common problem for clinicians. Although some hematological and bi-parametric magnetic resonance imaging (bpMRI) parameters might help increase the rate of positive prostate biops...
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Open AccessShape morphing of plastic films
Three-dimensional (3D) architectures have qualitatively expanded the functions of materials and flexible electronics. However, current fabrication techniques for devices constrain their substrates to 2D geomet...
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Open AccessDesign, synthesis and insecticidal activity and mechanism research of Chasmanthinine derivatives
Unrestricted reproduction and spread of pest had caused great damage to the quality and yield of crops in recent years. Besides the use of traditional chemical pesticides, natural products also make a huge con...
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Open AccessClimate change did not alter the effects of Bt maize on soil Collembola in northeast China
Bt maize is being increasingly cultivated worldwide as the effects of climate change are increasing globally. Bt maize IE09S034 and its near-isogenic non-Bt maize Zong 31 were used to investigate whether clima...
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Open AccessSMYD5 catalyzes histone H3 lysine 36 trimethylation at promoters
Histone marks, carriers of epigenetic information, regulate gene expression. In mammalian cells, H3K36me3 is mainly catalyzed by SETD2 at gene body regions. Here, we find that in addition to gene body regions,...
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Open AccessA multi-center study evaluating the correlation between meibomian gland dysfunction and depressive symptoms
Increased prevalence of depression has been found in patients with meibomian gland dysfunction (MGD); however, specific conditions of patients suffered from MGD and depression remains unclear. Our aim was to i...