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Primary and secondary transcriptional effects in the develo** human Down syndrome brain and heart

Down syndrome, caused by trisomic chromosome 21, is the leading genetic cause of mental retardation. Recent studies demonstrated that dosage-dependent increases in chromosome 21 gene expression occur in trisom...

Rong Mao, **aowen Wang, Edward L Spitznagel Jr, Laurence P Frelin… in Genome Biology (2005)