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  1. Article

    Open Access

    HDAC inhibitor ITF2357 reduces resistance of mutant-KRAS non-small cell lung cancer to pemetrexed through a HDAC2/miR-130a-3p-dependent mechanism

    Histone deacetylases (HDAC) contribute to oncogenic program, pointing to their inhibitors as a potential strategy against cancers. We, thus, studied the mechanism of HDAC inhibitor ITF2357 in resistance of mut...

    Jian Cui, Fei Xu, Wei Bai, Tiantian Zhao, Junbo Hong in Journal of Translational Medicine (2023)