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Article
Open AccessThe prognostic importance of jaundice in surgical resection with curative intent for gallbladder cancer
Preoperative jaundice is frequent in gallbladder cancer (GBC) and indicates advanced disease. Resection is rarely recommended to treat advanced GBC. An aggressive surgical approach for advanced GBC remains lac...
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Article
Open AccessSec13 Regulates Expression of Specific Immune Factors Involved in Inflammation In Vivo
The Sec13 protein functions in various intracellular compartments including the nuclear pore complex, COPII-coated vesicles and inside the nucleus as a transcription regulator. Here we developed a mouse model ...
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Article
Open AccessPredictors of responders to mononuclear stem cell-based therapeutic angiogenesis for no-option critical limb ischemia
Although the mononuclear cell (MNC) transplantation could theoretically induce therapeutic angiogenesis in the patients with no-option critical limb ischemia (NO-CLI), the clinical responses to this approach a...
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Article
Open AccessIdentification of diterpenoid compounds that interfere with Fli-1 DNA binding to suppress leukemogenesis
The ETS transcription factor Fli-1 controls the expression of genes involved in hematopoiesis including cell proliferation, survival, and differentiation. Dysregulation of Fli-1 induces hematopoietic and solid...
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Article
Open AccessLinc00423 as a tumor suppressor in retroperitoneal liposarcoma via activing MAPK signaling pathway through destabilizing of NFATC3
Unraveling the noncoding RNA expression networks governing cancer initiation and development is essential while remains largely uncompleted in retroperitoneal liposarcoma (RLS). Through RNA-seq technologies an...
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Article
Open AccessEffect of preoperative jaundice on long-term prognosis of gallbladder carcinoma with radical resection
This study was designed to evaluate the effect of preoperative jaundice on long-term prognosis of gallbladder carcinoma (GBC) after radical resection (R0).
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Article
Open AccessA preoperative mortality risk assessment model for Stanford type A acute aortic dissection
Acute aortic dissection type A is a life-threatening disease required emergency surgery during acute phase. Different clinical manifestations, laboratory tests, and imaging features of patients with acute aort...
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Article
Open AccessTherapeutic management of acute type A aortic intramural hematoma
The proper therapeutic management for acute type A aortic intramural hematoma (IMH) is still controversial. The purpose of this study was to compare the outcomes following emergency surgery or conservative tre...