4 Result(s)

Article

Structural basis for promiscuity in ligand recognition by yjdF riboswitch

Daniel Krochmal, Christina Roman, Anna Lewicka, Yaming Shao… in Cell Discovery (2024)

Article

A conserved RNA structural motif for organizing topology within picornaviral internal ribosome entry sites

Picornaviral IRES elements are essential for initiating the cap-independent viral translation. However, three-dimensional structures of these elements remain elusive. Here, we report a 2.84-Å resolution crysta...

Deepak Koirala, Yaming Shao, Yelena Koldobskaya, James R. Fuller… in Nature Communications (2019)

Article

Structural basis for activation of fluorogenic dyes by an RNA aptamer lacking a G-quadruplex motif

The DIR2s RNA aptamer, a second-generation, in-vitro selected binder to dimethylindole red (DIR), activates the fluorescence of cyanine dyes, DIR and oxazole thiazole blue (OTB), allowing detection of two well...

Sandip A. Shelke, Yaming Shao, Artur Laski, Deepak Koirala… in Nature Communications (2018)

Article

Synthesizing topological structures containing RNA

Though knotting and entanglement have been observed in DNA and proteins, their existence in RNA remains an enigma. Synthetic RNA topological structures are significant for understanding the physical and biolog...

Di Liu, Yaming Shao, Gang Chen, Yuk-Ching Tse-Dinh… in Nature Communications (2017)