-
Article
Open AccessInhibitory effect of curcumin on testosterone induced benign prostatic hyperplasia rat model
Benign prostatic hyperplasia (BPH) is one of the common male diseases, which is provoked by dihydrotestosterone (DHT) and androgen signals. Several studies showed that curcumin has various effects of preventio...
-
Article
Open AccessAssociation between polymorphisms of arachidonate 12-lipoxygenase (ALOX12) and schizophrenia in a Korean population
Arachidonic acid (AA), an essential polyunsaturated fatty acid, is one of the major components of neural membranes, which show an altered phospholipid composition in schizophrenia. Arachidonate 12-lipoxygenase (A...
-
Article
Open AccessNo association between polymorphisms of WNT2and schizophrenia in a Korean population
Wingless-type MMTV integration site family member 2 (WNT2) has a potentially important role in neuronal development; however, there has yet to be an investigation into the association between single nucleotide...
-
Article
Open AccessAssociation study of polymorphisms in synaptic vesicle-associated genes, SYN2 and CPLX2, with schizophrenia
The occurrence of aberrant functional connectivity in the neuronal circuit is one of the integrative theories of the etiology of schizophrenia. Previous studies have reported that the protein and mRNA levels o...
-
Article
Estrogen receptor-α gene haplotype is associated with primary knee osteoarthritis in Korean population
Estrogen and estrogen receptors (ERs) are known to play important roles in the pathophysiology of osteoarthritis (OA). To investigate ER-α gene polymorphisms for its associations with primary knee OA, we condu...
-
Article
Open AccessAngiotensin converting enzyme gene polymorphism in Korean patients with primary knee osteoarthritis
Angiotensin converting enzyme (ACE) plays an important role in the physiology of vasculature, blood pressure and inflammation. ACE gene, known to have insertion/deletion (I/D) polymorphism, has been widely inv...
-
Article
Open AccessEvaluation of a Apo-1/Fas promoter polymorphism in Korean stroke patients
Apoptosis has been implicated in the pathogenesis of neurodegenerative diseases such as stroke and Alzheimer's disease. Apo-1/Fas gene is one of the mediators of apoptosis in stroke. MvaI polymorphism is the f...
