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Article
Analysis between nitric oxide synthase 1 (NOS1) and risk of obesity
Nitric oxide (NO), which is produced by NO synthase (NOS), plays to modulate immune function, blood vessel dilatation, neurotransmission, and mechanism of toxicity. Here, we examined whether single nucleotide ...
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Article
Association study between monoamine oxidase A (MAOA) gene polymorphisms and schizophrenia: lack of association with schizophrenia and possible association with affective disturbances of schizophrenia
Monoamine oxidase A (MAOA) catalyzes monoamine neurotransmitters including dopamine, 5-hydroxytryptamine (5-HT, serotonin), and norepinephrine. MAOA also plays a key role in emotional regulation. The aim of th...
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Article
Genetic variants of GRIA1 are associated with susceptibility to schizophrenia in Korean population
The α-amino-3-hydroxy-5-methyl-4-propionic acid (AMPA) receptors are important for glutamate synaptic transmission in the central nervous system. Glutamate receptor, ionotropic, AMPA receptor 1 gene (GRIA1) belon...
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Article
Association of thrombospondin 1 gene with schizophrenia in Korean population
Thrombospondin 1 (THBS1), a multi-domain glycoprotein, is secreted from astrocytes and promotes synaptogenesis. Increasing evidence has suggested that not only various markers for synaptic pathology, but also ...
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Article
Polymorphisms of the Interferon gamma gene and coronary artery disease in the Korean population
Abundant evidence supports the hypothesis that inflammation plays an important role in the development of coronary artery disease (CAD). In this study, we investigated whether genetic polymorphisms of the Interfe...
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Article
Association of CTLA4, CD28 and ICOS gene polymorphisms with clinicopathologic characteristics of childhood IgA nephropathy in Korean population
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Article
Association of Niemann-Pick disease, type C2 (NPC2) polymorphisms with obesity in Korean population
Cholesterol homeostasis is essential for functional integrity of lipid. Niemann-Pick disease, type C2 (NPC2) encodes a protein containing a lipid recognition domain. NPC2 is related to regulation of cholesterol a...
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Article
Characterization of gene expression regulated by Panax ginseng in SH-SY5Y cells
To investigate the effects of Panax ginseng (PG) on SH-SY5Y human neuroblastoma cells, we profiled gene expressions of both normal and PG-treated groups using cDNA microarray. We performed 3-(4,5-dimethylthiazol-...