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Article
Open AccessIxeris dentata and Lactobacillus gasseri media protect against periodontitis through Nrf2-HO-1 signalling pathway
Periodontitis is an infectious inflammation in the gums characterized by loss of periodontal ligaments and alveolar bone. Its persistent inflammation could result in tooth loss and other health issues. Ixeris den...
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Article
Open AccessImpact of phenolic compounds in the acyl homoserine lactone-mediated quorum sensing regulatory pathways
Quorum sensing (QS) is a cell density-dependent regulation of virulent bacterial gene expression by autoinducers that potentially pertains in the epidemic of bacterial virulence. This study was initially desig...
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Article
Open AccessA new in vitro hemagglutinin inhibitor screening system based on a single-vesicle fusion assay
Hemagglutinin (HA) from the influenza virus plays a pivotal role in the infection of host mammalian cells and is, therefore, a druggable target, similar to neuraminidase. However, research involving the influe...
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Article
Open AccessHeterologous Production of the Marine Myxobacterial Antibiotic Haliangicin and Its Unnatural Analogues Generated by Engineering of the Biochemical Pathway
Despite their fastidious nature, marine myxobacteria have considerable genetic potential to produce novel secondary metabolites. The marine myxobacterium Haliangium ochraceum SMP-2 produces the antifungal polyket...