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Article
Open AccessA combinatorial genetic strategy for exploring complex genotype–phenotype associations in cancer
Available genetically defined cancer models are limited in genotypic and phenotypic complexity and underrepresent the heterogeneity of human cancer. Here, we describe a combinatorial genetic strategy applied t...
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Article
Open AccessEpigenetic signature of Gleason score and prostate cancer recurrence after radical prostatectomy
Identifying the subset of patients with clinically localized prostate cancer (PCa) at the highest risk of recurrence remains challenging, and better prognostic markers are needed. Gleason score is the best pre...