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Article
Open AccessA combinatorial genetic strategy for exploring complex genotype–phenotype associations in cancer
Available genetically defined cancer models are limited in genotypic and phenotypic complexity and underrepresent the heterogeneity of human cancer. Here, we describe a combinatorial genetic strategy applied t...
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Article
Copy number alterations are associated with metastatic-lethal progression in prostate cancer
Aside from Gleason score few factors accurately identify the subset of prostate cancer (PCa) patients at high risk for metastatic progression. We hypothesized that copy number alterations (CNAs), assessed usin...
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Article
The development and comparative effectiveness of a patient-centered prostate biopsy report: a prospective, randomized study
The prostate biopsy pathology report represents a critical document used for decision-making in patients diagnosed with prostate cancer, yet the content exceeds the health literacy of most patients. We sought ...
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Article
Coffee and tea consumption in relation to prostate cancer prognosis
Bioactive compounds found in coffee and tea may delay the progression of prostate cancer.
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Article
Open AccessMetformin use and prostate cancer in Caucasian men: results from a population-based case–control study
Metformin is a commonly used medication for type II diabetes mellitus. Epidemiologic studies have suggested a decreased relative risk of cancer with metformin use, and preclinical studies of prostate cancer (P...