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Copy number alterations are associated with metastatic-lethal progression in prostate cancer

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  1. Article

    Open Access

    A combinatorial genetic strategy for exploring complex genotype–phenotype associations in cancer

    Available genetically defined cancer models are limited in genotypic and phenotypic complexity and underrepresent the heterogeneity of human cancer. Here, we describe a combinatorial genetic strategy applied t...

    Shan Li, Alicia Wong, Huiyun Sun, Vipul Bhatia, Gerardo Javier… in Nature Genetics (2024)

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  2. Article

    Open Access

    Long non-coding RNAs identify a subset of luminal muscle-invasive bladder cancer patients with favorable prognosis

    Muscle-invasive bladder cancer (MIBC) is a heterogeneous disease, and gene expression profiling has identified several molecular subtypes with distinct biological and clinicopathological characteristics. While...

    Joep J. de Jong, Yang Liu, A. Gordon Robertson, Roland Seiler… in Genome Medicine (2019)

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  3. Article

    Open Access

    Metformin use and prostate cancer in Caucasian men: results from a population-based case–control study

    Metformin is a commonly used medication for type II diabetes mellitus. Epidemiologic studies have suggested a decreased relative risk of cancer with metformin use, and preclinical studies of prostate cancer (P...

    Jonathan L. Wright, Janet L. Stanford in Cancer Causes & Control (2009)

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