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Automation of Fluorescent Differential Display With Digital Readout
Since its invention in 1992, differential display (DD) has become the most commonly used technique for identifying differentially expressed genes because of its many advantages over competing technologies such...
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Article
A protocol for differential display of mRNA expression using either fluorescent or radioactive labeling
Since its invention in the early 1990s, differential display (DD) has become one of the most commonly used techniques for identifying differentially expressed genes at the mRNA level. Unlike other genomic appr...
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Protocol
Automated Fluorescent Differential Display for Cancer Gene Profiling
Since its invention in 1992, differential display (DD) has become the most commonly used technique for identifying differentially expressed genes because of its many advantages over competing technologies such...
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Article
Proof-reading signal accuracy of gene expression by binary differential display
Differential display (DD) is commonly used for identifying differentially expressed genes. However, each cDNA species identified by DD must be verified so a “real difference” can be differentiated from false p...
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Article
Linear dynamic range for signal detection in fluorescent differential display
We have determined the linear dynamic range in signal detection by Fluorescent Differential Display (FDD) using conditionally induced mRNA expression of the p53 tumor-suppressor gene as a control. By serial sp...
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Article
Open AccessTrivalent soluble TNF Receptor, a potent TNF-α antagonist for the treatment collagen-induced arthritis
Tumor necrosis factor is a major pro-inflammatory cytokine which triggers various physiological consequences by binding to and trimerizing its receptors, and has been the single most sought-after drug target f...
