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    Chapter

    Mechanisms of Resistance to Ionising Radiations: Genetic and Molecular Studies on Ataxia-Telangiectasia and Related Radiation-Sensitive Mutants

    In mammalian cells the mechanisms of resistance to damage caused by ionising radiations (IR) are largely unknown. Knowledge of the types of damage induced and of the enzymes, identified mostly in lower organis...

    John Thacker, Reg Wilkinson, Anil Ganesh… in DNA Repair Mechanisms and Their Biological… (1989)

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    Article

    Mammalian recombination-repair genes XRCC2 and XRCC3 promote correct chromosome segregation

    Growth and development are dependent on the faithful duplication of cells. Duplication requires accurate genome replication, the repair of any DNA damage, and the precise segregation of chromosomes at mitosis;...

    Carol S. Griffin, Paul J. Simpson, Caroline R. Wilson, John Thacker in Nature Cell Biology (2000)