4 Result(s)
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John Essandoh
Science, Humanities and Social Sciences, multidisciplinary
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Article
Open AccessSignatures of adaptation at key insecticide resistance loci in Anopheles gambiae in Southern Ghana revealed by reduced-coverage WGS
Resistance to insecticides and adaptation to a diverse range of environments present challenges to Anopheles gambiae s.l. mosquito control efforts in sub-Saharan Africa. Whole-genome-sequencing is often employed ...
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Article
Open AccessGenome-wide association studies reveal novel loci associated with pyrethroid and organophosphate resistance in Anopheles gambiae and Anopheles coluzzii
Resistance to insecticides in Anopheles mosquitoes threatens the effectiveness of malaria control, but the genetics of resistance are only partially understood. We performed a large scale multi-country genome-wid...
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Article
Open AccessA high throughput multi-locus insecticide resistance marker panel for tracking resistance emergence and spread in Anopheles gambiae
The spread of resistance to insecticides in disease-carrying mosquitoes poses a threat to the effectiveness of control programmes, which rely largely on insecticide-based interventions. Monitoring mosquito pop...
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Article
Open AccessAdaptive introgression between Anopheles sibling species eliminates a major genomic island but not reproductive isolation
Adaptive introgression can provide novel genetic variation to fuel rapid evolutionary responses, though it may be counterbalanced by potential for detrimental disruption of the recipient genomic background. We...
