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    Direct enzymatic sequencing of 5-methylcytosine at single-base resolution

    5-methylcytosine (5mC) is the most important DNA modification in mammalian genomes. The ideal method for 5mC localization would be both nondestructive of DNA and direct, without requiring inference based on de...

    Tong Wang, Johanna M. Fowler, Laura Liu, Christian E. Loo… in Nature Chemical Biology (2023)