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Article
Open AccessUSP11 regulates proliferation and apoptosis of human spermatogonial stem cells via HOXC5-mediated canonical WNT/β-catenin signaling pathway
Spermatogonial stem cells (SSCs) are capable of transmitting genetic information to the next generations and they are the initial cells for spermatogenesis. Nevertheless, it remains largely unknown about key g...
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Article
Open AccessCDCA5-EEF1A1 interaction promotes progression of clear cell renal cell carcinoma by regulating mTOR signaling
Cell division cycle associated 5 (CDCA5) plays ontogenetic role in various human cancers. However, its specific function and regulatory mechanism in ccRCC remain uncertain.
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Article
Open AccessCorrection: CircZNF215 promotes tumor growth and metastasis through inactivation of the PTEN/AKT pathway in intrahepatic cholangiocarcinoma
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Article
Open AccessFumarate induces LncRNA-MIR4435-2HG to regulate glutamine metabolism remodeling and promote the development of FH-deficient renal cell carcinoma
Fumarate hydratase (FH) deficient renal cell carcinoma (RCC) is a type of tumor with definite metabolic disorder, but the mechanism of metabolic remodeling is still unclear. LncRNA was reported to closely corr...
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Article
Safety and efficacy of laparoscopic transperitoneal versus retroperitoneal resection for benign retroperitoneal tumors: a retrospective cohort study
Benign retroperitoneal tumors (BRTs) are clinically rare solid tumors. This study aimed to compare the safety and efficacy of laparoscopic transperitoneal versus retroperitoneal resection for BRTs.
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Article
A task allocation and pricing mechanism based on Stackelberg game for edge-assisted crowdsensing
With the rapid development and growing popularity of Internet of Things (IoT), edge-assisted crowdsensing has emerged as a new mode of data collection and data processing. In an edge-assisted crowdsensing syst...
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Article
Open AccessMDIG-mediated H3K9me3 demethylation upregulates Myc by activating OTX2 and facilitates liver regeneration
The mineral dust-induced gene (MDIG) comprises a conserved JmjC domain and has the ability to demethylate histone H3 lysine 9 trimethylation (H3K9me3). Previous studies have indicated the significance of MDIG ...
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Article
Open AccessCorrection: CircNFIB inhibits tumor growth and metastasis through suppressing MEK1/ERK signaling in intrahepatic cholangiocarcinoma
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Article
Open AccessJoint DNN partitioning and task offloading in mobile edge computing via deep reinforcement learning
As Artificial Intelligence (AI) becomes increasingly prevalent, Deep Neural Networks (DNNs) have become a crucial tool for develo** and advancing AI applications. Considering limited computing and energy res...
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Article
Open AccessAn intelligent approach of task offloading for dependent services in Mobile Edge Computing
With the growing popularity of Internet of Things (IoT), Mobile Edge Computing (MEC) has emerged for reducing the heavy workload at the multi-cloud core network by deploying computing and storage resources at ...
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Article
Open AccessSerum extracellular vesicles derived hsa-miR-320d as an indicator for progression of clear cell renal cell carcinoma
Renal cell carcinoma (RCC) is a prevalent malignancy with a rising incidence in develo** countries. Clear cell renal cell carcinoma (ccRCC) constitutes 70% of RCC cases and is prone to metastasis and recurre...
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Article
Open AccessCircZNF215 promotes tumor growth and metastasis through inactivation of the PTEN/AKT pathway in intrahepatic cholangiocarcinoma
Increasing evidence shows that circular RNAs (circRNAs), a novel class of noncoding RNAs, play a crucial role in the development of cancers, including intrahepatic cholangiocarcinoma (iCCA). Nevertheless, thei...
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Article
Open AccessCorrection: NCSTN promotes hepatocellular carcinoma cell growth and metastasis via β-catenin activation in a Notch1/AKT dependent manner
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Article
Trocar layouts in laparoscopic liver surgery
Since the first laparoscopic wedge resection reported by Reich, laparoscopic liver resection (LLR) has been progressively developed, acquiring safety and feasibility. The time has witnessed a milestone leap fo...
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Article
Open AccessCollaborative task offloading and resource allocation with hybrid energy supply for UAV-assisted multi-clouds
Cloud computing has emerged as a promising paradigm for meeting the growing resource demands of Internet of Things (IoT) devices. Meanwhile, with the popularity of mobile aerial base stations, Unmanned Aerial ...
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Article
Open AccessVHL and DNA damage repair pathway alterations as potential clinical biomarkers for first-line TKIs in metastatic clear cell renal cell carcinomas
Vascular endothelial growth factor receptor tyrosine kinase inhibitors (VEGFR-TKIs) are being used for the first-line treatment of metastatic clear cell renal cell carcinoma (mccRCC). Here, we set out to explo...
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Article
Analyzing the interactions among factors affecting cloud adoption for software testing: a two-stage ISM-ANN approach
To reduce costs and improve organizational efficiency, the adoption of innovative services such as Cloud services is the current trend in today’s highly competitive global business venture. The aim of the stud...
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Article
Practitioner’s view of the success factors for software outsourcing partnership formation: an empirical exploration
Software Outsourcing Partnership (SOP) is a client-vendor relationship focused solely on mutual trust and dedication that achieves mutually beneficial objectives. Often, a well-established outsourcing relation...
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Article
Open AccessCircNFIB inhibits tumor growth and metastasis through suppressing MEK1/ERK signaling in intrahepatic cholangiocarcinoma
Considerable evidence shows that circular RNAs (circRNAs) play an important role in tumor development. However, their function in intrahepatic cholangiocarcinoma (ICC) metastasis and the underlying mechanisms ...
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Article
Edge User Allocation in Overlap Areas for Mobile Edge Computing
The rapid development of mobile communication technology has promoted the emergence of mobile edge computing (MEC), which allows mobile users to transfer their computing tasks to nearby edge servers to reduce ...