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  1. Article

    Open Access

    Ferroptotic alveolar epithelial type II cells drive TH2 and TH17 mixed asthma triggered by birch pollen allergen Bet v 1

    Asthma is a common allergic disease characterized by airway hypersensitivity and airway remodeling. Ferroptosis is a regulated death marked by iron accumulation and lipid peroxidation. Several environmental po...

    Linyi Ma, Ying He, Huancheng **e, **g Wang, Jiaqian Chen in Cell Death Discovery (2024)

  2. Article

    Open Access

    TSSK4 upregulation in alveolar epithelial type-II cells facilitates pulmonary fibrosis through HSP90-AKT signaling restriction and AT-II apoptosis

    Alveolar epithelial injury is one of the important pathological changes in idiopathic pulmonary interstitial fibrosis (IPF), but the regulatory mechanism remains unclear. Here, we reported that alveolar epithe...

    Huifang Chen, Andong He, Haoyang Li, Honglv Chen, in Cell Death & Disease (2021)