51 Result(s)
within
JianHua Wang
English
Microbiology
-
Article
Open AccessPharmacokinetics and pharmacodynamics of antibacterial peptide NZX in Staphylococcus aureus mastitis mouse model
Staphylococcus aureus is associated with dairy mastitis, which causes serious economic losses to dairy farming industry. Antibacterial peptide NZX showed good antibacterial activity against S. aureus. This study ...
-
Article
Open AccessExpression and characterization of the new antimicrobial peptide AP138L-arg26 anti Staphylococcus aureus
The low activity and yield of antimicrobial peptides (AMPs) are pressing problems. The improvement of activity and yield through modification and heterologous expression, a potential way to solve the problem, ...
-
Article
Lactoferrin, a Great Wall of host-defence?
-
Article
Effects of dietary supplementation of bovine lactoferrin on growth performance, immune function and intestinal health in weaning piglets
Weaning is a crucial period in the pig’s life cycle, which is frequently followed by gastrointestinal (GI) infections, diarrhea and even death. This study focused on the impact of bovine lactoferrin (bLF) supp...
-
Article
Open AccessC-terminal mini-PEGylation of a marine peptide N6 had potent antibacterial and anti-inflammatory properties against Escherichia coli and Salmonella strains in vitro and in vivo
Enteropathogenic Escherichia coli and Salmonella pullorum are two important groups of zoonotic pathogens. At present, the treatment of intestinal pathogenic bacteria infection mainly relies on antibiotics, which ...
-
Article
Antibacterial peptide NZ2114-loaded hydrogel accelerates Staphylococcus aureus-infected wound healing
Wound infection caused by Staphylococcus aureus (S. aureus) is a great challenge which has caused significant burden and economic loss to the medical system. NZ2114, a plectasin-derived peptide, is an antibacteri...
-
Article
Resistance response to Arenicin derivatives in Escherichia coli
The rising prevalence of antibiotic resistance poses the greatest health threats. Antimicrobial peptides (AMPs) are regarded as the potentially effective therapy. To avoid current crisis of antibiotic resistan...
-
Article
A study on fungal defensin against multidrug-resistant Clostridium perfringens and its treatment on infected poultry
In the present study, we aimed to investigate the antibacterial activity and mechanisms of plectasin-derived peptide NZ2114 in vitro and its therapeutic effects in vivo on broilers challenged with Clostridium per...
-
Article
Fatty acid modified-antimicrobial peptide analogues with potent antimicrobial activity and topical therapeutic efficacy against Staphylococcus hyicus
There is an urgent need to explore new antimicrobial agents due to the looming threat of bacteria resistance. Bovine lactoferricin (LfcinB), as a multifunctional peptide, has the potential to be a new active d...
-
Article
Effect of the environmental factors on diketopiperazine cyclo(Pro-Phe) production and antifungal activity of Bacillus amyloliquefaciens Q-426
Bacillus amyloliquefaciens Q-426 with strong antifungal activity was isolated from the compost samples in Dalian of China. Four kinds of diketopiperazines were extracted from the strain including cyclo(Pro-Phe) (...
-
Article
Open AccessSeed biostimulant Bacillus sp. MGW9 improves the salt tolerance of maize during seed germination
Crop performance is seriously affected by high salt concentrations in soils. To develop improved seed pre-sowing treatment technologies, it is crucial to improve the salt tolerance of seed germination. Here, w...
-
Article
Potent intracellular antibacterial activity of a marine peptide-N6NH2 and its D-enantiomer against multidrug-resistant Aeromonas veronii
Aeromonas veronii can cause a variety of diseases such as sepsis in humans and animals. However, there has been no effective way to eradicate A. veronii. In this study, the intracellular antibacterial activities ...
-
Article
Responses of Ammonia-Oxidizing Archaea and Bacteria in Malodorous River Sediments to Different Remediation Techniques
In this study, the joint use of high throughput sequencing, real-time quantitative PCR, and ammonia-oxidizing bacteria (AOB)–inhibiting allylthiourea was used to differentiate between the contributions of ammo...
-
Article
A recombinant fungal defensin-like peptide-P2 combats Streptococcus dysgalactiae and biofilms
Streptococcus dysgalactiae, considered one of the main pathogens that causes bovine mastitis, is a serious threat to humans and animals. However, the excessive use of antibiotics and the characteristic of S. dysg...
-
Article
Therapeutic potential of a designed CSαβ peptide ID13 in Staphylococcus aureus-induced endometritis of mice
Staphylococcus aureus is a common pathogen that can cause clinical and subclinical endometritis in humans and animals. In this study, a designed CSαβ peptide ID13 from DLP4 exhibited high stable antibacterial act...
-
Article
A new high-yielding antimicrobial peptide NZX and its antibacterial activity against Staphylococcus hyicus in vitro/vivo
Staphylococcus hyicus, considered as a leading pathogen of exudative epidermitis, is a serious threat to humans and animals. The emergency of bacterial resistance to antibiotics, especially in human and animal he...
-
Article
Dynamics of nitrogen transformation and bacterial community with different aeration depths in malodorous river
In this research, the dynamics of nitrogen transformation and bacterial community in malodorous river were investigated with different aeration depths. Computational flow dynamics (CFD) and Reynolds number (Re...
-
Article
Biodegradation of mycotoxin fumonisin B1 by a novel bacterial consortium SAAS79
Fumonisin B1 (FB1) contamination in cereals and cereal products remains an important aspect of food safety because of its wide distribution and the potential health hazard. However, only a few microorganisms h...
-
Article
A recombinant fungal defensin-like peptide-P2 combats multidrug-resistant Staphylococcus aureus and biofilms
There is an urgent need to discover new active drugs to combat methicillin-resistant Staphylococcus aureus, which is a serious threat to humans and animals and incompletely eliminated by antibiotics due to its in...
-
Article
Phosphorylation by Prp4 kinase releases the self-inhibition of FgPrp31 in Fusarium graminearum
Prp31 is one of the key tri-snRNP components essential for pre-mRNA splicing although its exact molecular function is not well studied. In a previous study, suppressor mutations were identified in the PRP31 ortho...
