552 Result(s)
within
Jian-** Hong
Life Sciences
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Article
Open AccessIncreased ONECUT2 induced by Helicobacter pylori promotes gastric cancer cell stemness via an AKT-related pathway
Helicobacter pylori (HP) infection initiates and promotes gastric carcinogenesis. ONECUT2 shows promise for tumor diagnosis, prognosis, and treatment. This study explored ONECUT2’s role and the specific mechanism...
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Structural elucidation a complex galactosyl and glucosyl-rich pectin from the pericarp of immature fruits of Juglans mandshurica Maxim.
A glucosyl-rich pectin, JMMP-3 (Mw, 2.572 × 104 g/mol, O-methyl % = 3.62%), was isolated and purified from the pericarp of the immature fruit of Juglans mandshurica Maxim. (QingLongYi). The structure of JMMP-3 wa...
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Shoot and Root Traits are Associated with Varying Soil Phosphorus Supply in Chinese Cabbage
Purpose: Phosphorus (P) is an essential nutrient for crop growth. P absorption efficiency was closely correlated with the variety of crop traits. It is currently unclear how vegetable crops may adapt to variou...
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Open AccessThe MYB family and their response to abiotic stress in ginger (Zingiber officinale Roscoe)
Zingiber officinale Roscoe, colloquially known as ginger, is a crop of significant medicinal and culinary value that frequently encounters adversity stemming from inhospitable environmental conditions. The MYB tr...
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Metagenomic analysis of individual mosquito viromes reveals the geographical patterns and drivers of viral diversity
Mosquito transmitted viruses are responsible for an increasing burden of human disease. Despite this, little is known about the diversity and ecology of viruses within individual mosquito hosts. Here, using a ...
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Open AccessGenome-wide analysis and expression profiling of the HD-ZIP gene family in kiwifruit
The homeodomain-leucine zipper (HD-Zip) gene family plays a pivotal role in plant development and stress responses. Nevertheless, a comprehensive characterization of the HD-Zip gene family in kiwifruit has bee...
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Open AccessCsn5 inhibits autophagy by regulating the ubiquitination of Atg6 and Tor to mediate the pathogenicity of Magnaporthe oryzae
Csn5 is subunit 5 of the COP9 signalosome (CSN), but the mechanism by which it strictly controls the pathogenicity of pathogenic fungi through autophagy remains unclear. Here, we found that Csn5 deficiency att...
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Open AccessCorrection: Loss of ferroportin induces memory impairment by promoting ferroptosis in Alzheimer’s disease
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Establishment of in vitro pollen germination system in C4 model plant Foxtail Millet
The development and germination of pollen play crucial roles in the sexual reproduction of plants, and this process holds great potential for improving grain yield in crops. In this study, we established a ger...
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Article
Endothelial extracellular vesicles induce acute lung injury via follistatin-like protein 1
Cardiopulmonary bypass has been speculated to elicit systemic inflammation to initiate acute lung injury (ALI), including acute respiratory distress syndrome (ARDS), in patients after cardiac surgery. We previ...
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Kinase PIM1 governs ferroptosis to reduce retinal microvascular endothelial cell dysfunction triggered by high glucose
Previous studies have implicated targeting Pim-1 proto-oncogene, serine/threonine kinase (PIM1) as a preventive measure against high glucose–induced cellular stress and apoptosis. This study aimed to reveal th...
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Open AccessIntegrating patch stability and network connectivity to optimize ecological security pattern
Designing and optimizing ecological security pattern (ESP) is an effective solution to formulate landscape planning. The commonly used network analysis for ESP optimization abstracts ecological sources and eco...
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Open Accessm6A-methylated KCTD21-AS1 regulates macrophage phagocytosis through CD47 and cell autophagy through TIPR
Blocking immune checkpoint CD47/SIRPα is a useful strategy to engineer macrophages for cancer immunotherapy. However, the roles of CD47-related noncoding RNA in regulating macrophage phagocytosis for lung canc...
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Open AccessAbnormal protein post-translational modifications induces aggregation and abnormal deposition of protein, mediating neurodegenerative diseases
Protein post-translational modifications (PPTMs) refer to a series of chemical modifications that occur after the synthesis of protein. Proteins undergo different modifications such as phosphorylation, acetyla...
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Retraction Note: Autophagy regulated by lncRNA HOTAIR contributes to the cisplatin-induced resistance in endometrial cancer cells
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Open AccessmiR-277 targets the proapoptotic gene-hid to ameliorate Aβ42-mediated neurodegeneration in Alzheimer’s model
Alzheimer’s disease (AD), an age-related progressive neurodegenerative disorder, exhibits reduced cognitive function with no cure to date. One of the reasons for AD is the accumulation of Amyloid-beta 42 (Aβ42...
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Open AccessComparative transcriptomic analysis of salivary glands between the zoophytophagous Cyrtorhinus lividipennis and the phytozoophagous Apolygus lucorum
Saliva plays a crucial role in sha** the feeding behavior of insects, involving processes such as food digestion and the regulation of interactions between insects and their hosts. Cyrtorhinus lividipennis serv...
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Open AccessThe cell cycle, autophagy, and cell wall integrity pathway jointly governed by MoSwe1 in Magnaporthe oryzae
The cell cycle is pivotal to cellular differentiation in plant pathogenic fungi. Cell wall integrity (CWI) signaling plays an essential role in co** with cell wall stress. Autophagy is a degradation process ...
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Chromosome-scale assembly and gene editing of Solanum americanum genome reveals the basis for thermotolerance and fruit anthocyanin composition
Solanum americanum serves as a promising source of resistance genes against potato late blight and is considered as a leafy vegetable for complementary food and nutrition. The limited availability of high-quality...
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Crystallographic and biochemical analyses of a far-red allophycocyanin to address the mechanism of the super-red-shift
Far-red absorbing allophycocyanins (APC), identified in cyanobacteria capable of FRL photoacclimation (FaRLiP) and low-light photoacclimation (LoLiP), absorb far-red light, functioning in energy transfer as li...
