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Article
Open AccessImpact of CEO’s scientific research background on the enterprise digital level
Leveraging the Chinese capital market, we investigate the relationship between a CEO’s scientific research background and the level of digitalization within enterprises. Our results demonstrate robust findings...
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Article
Open AccessMulti-omic analysis reveals the effects of interspecific hybridization on the synthesis of seed reserve polymers in a Triticum turgidum ssp. durum × Aegilops sharonensis amphidiploid
Wheat grain endosperm is mainly composed of proteins and starch. The contents and the overall composition of seed storage proteins (SSP) markedly affect the processing quality of wheat flour. Polyploidization ...
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Article
Open AccessIntegration of transcriptomics, metabolomics, and hormone analysis revealed the formation of lesion spots inhibited by GA and CTK was related to cell death and disease resistance in bread wheat (Triticum aestivum L.)
Wheat is one of the important grain crops in the world. The formation of lesion spots related to cell death is involved in disease resistance, whereas the regulatory pathway of lesion spot production and resis...
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Article
Open AccessCombined algorithms of high-frequency topographical effects for the boundary-value problems based on Helmert's second condensation method
The Helmert’s second condensation method is usually used to condense the topographical masses outside the boundary surface in the determination of the geoid and quasi-geoid based on the boundary-value theory. ...
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Open AccessCountry-specific determinants for COVID-19 case fatality rate and response strategies from a global perspective: an interpretable machine learning framework
There are significant geographic inequities in COVID-19 case fatality rates (CFRs), and comprehensive understanding its country-level determinants in a global perspective is necessary. This study aims to quant...
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Cell division cycle 42 attenuates high glucose-treated renal tubular epithelial cell apoptosis, fibrosis, and inflammation, but activates the PAK1/AKT pathway
Cell division cycle 42 (CDC42) modulates metabolism, inflammation, and fibrosis to engage in the pathology of diabetic complications. This study intended to further investigate the influence of CDC42 on viabil...
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Article
A deep learning method for recommending university patents to industrial clusters by common technological needs mining
Industrial clusters, geographical concentrations of interconnected companies, aim to achieve technological innovation by acquiring common technology, which is the technology shared by all companies in an indus...
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Article
Controlling citrus Huanglongbing based on soil remediation and biocontrol
Huanglongbing (HLB) is a devastating citrus disease that causes significant financial losses in the citrus industry. However, there is no cure by current control strategies. Damaged soils were observed in citr...
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Open AccessSeismic Risk Model for the Bei**g–Tian**–Hebei Region, China: Considering Epistemic Uncertainty from the Seismic Hazard Models
This study presents a probabilistic seismic risk model for the Bei**g–Tian**–Hebei region in China. The model comprises a township-level residential building exposure model, a vulnerability model derived fro...
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Genome-wide identification of the basic leucine zipper transcription factor genes related to starch synthesis in wheat (Triticum aestivum L.)
In plants, the basic leucine zipper (bZIP) family of transcription factors is known for its large size and diversity. Many studies have shown that bZIP transcription factors play an indispensable role in the g...
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Article
Development of an SI-traceable N-terminal pro-B-type natriuretic peptide certified reference material using structure-based impurity-corrected isotope dilution mass spectrometry approaches
N-Terminal pro-B-type natriuretic peptide (NT-proBNP) is a pivotal biomarker for the diagnosis and prognosis of heart failure (HF). However, no SI-traceable certified reference material (CRM) or reference meas...
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Article
GAGE-seq concurrently profiles multiscale 3D genome organization and gene expression in single cells
The organization of mammalian genomes features a complex, multiscale three-dimensional (3D) architecture, whose functional significance remains elusive because of limited single-cell technologies that can conc...
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Open AccessMulti-omics analysis revealed that the protein kinase MoKin1 affected the cellular response to endoplasmic reticulum stress in the rice blast fungus, Magnaporthe oryzae
Previous studies have shown that protein kinase MoKin1 played an important role in the growth, conidiation, germination and pathogenicity in rice blast fungus, Magnaporthe oryzae. ΔMokin1 mutant showed significan...
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Article
scGHOST: identifying single-cell 3D genome subcompartments
Single-cell Hi-C (scHi-C) technologies allow for probing of genome-wide cell-to-cell variability in three-dimensional (3D) genome organization from individual cells. Computational methods have been developed t...
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Article
Open AccessOrigin and dispersal history of Hepatitis B virus in Eastern Eurasia
Hepatitis B virus is a globally distributed pathogen and the history of HBV infection in humans predates 10000 years. However, long-term evolutionary history of HBV in Eastern Eurasia remains elusive. We prese...
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Article
Open AccessLIN28B induced PCAT5 promotes endometrial cancer progression and glycolysis via IGF2BP3 deubiquitination
Endometrial cancer (EC) cells exhibit abnormal glucose metabolism, characterized by increased aerobic glycolysis and decreased oxidative phosphorylation. Targeting cellular glucose metabolism in these cells co...
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Author Correction: Potent suppression of neuroendocrine tumors and gastrointestinal cancers by CDH17CAR T cells without toxicity to normal tissues
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Article
Open AccessSingle-shot readout of a superconducting qubit using a thermal detector
Measuring the state of a qubit is a key fundamental operation of a quantum computer. High-fidelity single-shot readout of superconducting qubits can be achieved using parametric amplifiers at millikelvin tempe...
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Article
Three-dimensional finite element analysis on stress distribution after different palatoplasty and levator veli palatini muscle reconstruction
To establish a three-dimensional finite element model of the upper palate, pharyngeal cavity, and levator veli palatini muscle in patients with unilateral complete cleft palate, simulate two surgical procedure...
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Article
Open AccessContribution of irreversible non-180° domain to performance for multiphase coexisted potassium sodium niobate ceramics
Despite the dominance of lead-based piezoelectric materials with ultrahigh electric-field-induced strain in actuating applications, seeking eco-friendly substitutes with an equivalent performance remains an ur...
