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Article
Open AccessA multi-kingdom collection of 33,804 reference genomes for the human vaginal microbiome
The human vagina harbours diverse microorganisms—bacteria, viruses and fungi—with profound implications for women’s health. Genome-level analysis of the vaginal microbiome across multiple kingdoms remains limi...
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Article
Open AccessConservative versus liberal oxygen therapy for intensive care unit patients: meta-analysis of randomized controlled trials
It remains unclear whether conservative oxygen therapy (COT) or liberal oxygen therapy (LOT) is more beneficial to the clinical outcomes of intensive care unit (ICU) patients. We systematically reviewed the ef...
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Article
Open AccessIdentification of key genes for atherosclerosis in different arterial beds
Atherosclerosis (AS) is the pathologic basis of various cardiovascular and cerebrovascular events, with a high degree of heterogeneity among different arterial beds. However, mechanistic differences between ar...
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Article
Open AccessUltrasonic AccV: a potential indicator of peripheral arteriosclerosis in patients with chronic obstructive pulmonary disease
This study aimed to investigate the risk factors for peripheral arteriosclerosis (PAS) and peripheral artery disease (PAD) in chronic obstructive pulmonary disease (COPD) patients and potential ultrasound indi...
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Article
Open AccessExploring the problems and co** strategies of pharmacy internship in large general hospitals in China: from the perspective of preceptors
The role of the Hospital Pharmacy Preceptor (HPP) is pivotal in upholding the excellence of experiential training and fostering the professional growth of pharmacy interns. However, there is a lack of studies ...
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Article
Open AccessDaily rhythm of urban space usage: insights from the nexus of urban functions and human mobility
As urban density increases, it becomes increasingly common for multiple functions to coexist within the same space, intensifying the complexity of human activity dynamics. However, traditional urban zoning, wh...
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Chapter and Conference Paper
Rigid-Flexible Coupling Dynamics Analysis of Boom-Hoisting System of Wind Power Crane
Based on the slenderness of wind power crane boom and the complexity of working environment, a mathematical model of rigid-flexible coupling dynamics including wind load and vibration characteristic analysis i...
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Article
Open AccessTrends in migraine incidence among women of childbearing age from 1990 to 2019 and the prediction for 2030: an analysis of national data in China
Migraine is a primary headache, which has been producing heavy disease burden globally. There is no data on the incidence of migraine among women of childbearing age worldwide, including China. This study aime...
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Article
Open AccessAg nanocomposite hydrogels with immune and regenerative microenvironment regulation promote scarless healing of infected wounds
Bacterial infection, complex wound microenvironment and persistent inflammation cause delayed wound healing and scar formation, thereby disrupting the normal function and appearance of skin tissue, which is on...
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Article
Open AccessExtreme diversity of 12 cations in folding ALS-linked hSOD1 unveils novel hSOD1-dependent mechanisms for Fe2+/Cu2+-induced cytotoxicity
153-Residue copper-zinc superoxide dismutase 1 (hSOD1) is the first gene whose mutation was linked to FALS. To date, > 180 ALS-causing mutations have been identified within hSOD1, yet the underlying mechanism ...
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Article
Open AccessAnalysis of the static and dynamic characteristics of the electro-hydraulic pressure servo valve of robot
In this study, we comprehensively investigate the structure and operational principles of the Rotary Direct Drive Electro-Hydraulic Pressure Servo Valve (RDDPV). Our objective is to establish the dynamics equa...
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Article
Open AccessATP induces folding of ALS-causing C71G-hPFN1 and nascent hSOD1
ALS-causing C71G-hPFN1 coexists in both folded and unfolded states, while nascent hSOD1 is unfolded. So far, the mechanisms underlying their ALS-triggering potential remain enigmatic. Here we show by NMR that ...
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Article
Open AccessApplication of bilingual simulated patients in the medical history collection for international medical students in China
In all international medical student (IMS) programs in China, language barriers between IMSs and Chinese patients greatly reduced the learning in clinical practice and brought great challenges to IMSs in their...
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Article
Open AccessUse of machine learning to assess the prognostic utility of radiomic features for in-hospital COVID-19 mortality
As portable chest X-rays are an efficient means of triaging emergent cases, their use has raised the question as to whether imaging carries additional prognostic utility for survival among patients with COVID-...
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Article
Open AccessDependency of NELF-E-SLUG-KAT2B epigenetic axis in breast cancer carcinogenesis
Cancer cells undergo transcriptional reprogramming to drive tumor progression and metastasis. Using cancer cell lines and patient-derived tumor organoids, we demonstrate that loss of the negative elongation fa...
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Article
Open AccessC,N co-doped TiO2 hollow nanofibers coated stainless steel meshes for oil/water separation and visible light-driven degradation of pollutants
Complex pollutants are discharging and accumulating in rivers and oceans, requiring a coupled strategy to resolve pollutants efficiently. A novel method is proposed to treat multiple pollutants with C,N co-dop...
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Article
Open AccessSoundscape in city and built environment: current developments and design potentials
In the field of environmental acoustics, the conventional approach of reducing ‘sound level’ does not always deliver the required improvements in quality of life. Soundscape, defined by the ISO as the ‘acousti...
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Article
Open AccessOn the definition of noise
Urbanization has exposed people to extreme sound levels. Although researchers have investigated the ability of people to listen, analyze, and distinguish sound, the concept of noise has not been clearly articu...
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Article
Open AccessWhat do we visually focus on in a World Heritage Site? A case study in the Historic Centre of Prague
Since socio-economic development is associated with artificial construction, heritage environments must be protected and renewed while adapting to such development. Many World Heritage Sites’ visual integrity ...
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Article
Open AccessDevelopment of acoustic computer simulation for performance spaces: A systematic review and meta-analysis
This article aims to review the development of acoustic computer simulation for performance spaces. The databases of Web of Science and Scopus were searched for peer-reviewed journal articles published in Engl...
