8,115 Result(s)
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Article
Colonic inhibition of gastric secretion in man
The effect of colonic infusion of various solutions on submaximal pentagastrin-stimulated gastric secretion was determined in healthy volunteers. Hypertonic (823 mOsm/kg) glucose, mannitol, and saline, and als...
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Article
Isotope studies in gastric emptying
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Article
Gastric emptying and intragastric distribution of lipids in man
We measured gastric emptying of fat and water from a solid-liquid meal in healthy volunteers using a tubeless scintigraphic method. Selenium-75 glycerol triether, incorporated in butter, was the lipid-phase ma...
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Article
Gastric bleeding and gastric secretion with sulindac and naproxen
We have examined concurrent gastric secretory rates and bleeding by a gastric wash technique during treatment with naproxen, sulindac, and placebo. Twelve subjects, in each of 4 treatment periods, took either ...
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Article
Comparative in vitro antitumor activity of homoharringtonine and harringtonine against clonogenic human tumor cells
Harringtonine and its derivative homoharringtonine are ester-containing anti-leukemic alkaloids isolated from the tree Cephalotaxus harringtonia. In order to compare their antitumor activity against solid tumo...
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Article
Antitumor activity of didemnin B in the human tumor stem cell assay
In vitro studies of the schedule dependency and cytotoxicity of didemnin B, a novel depsipeptide isolated from a Carribean tunicate (Didemnidae), were carried out in fresh tumor cells obtained from biopsies fr...
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Article
Inhibition of human breast cancer colony formation by anticalmodulin agents: Trifluoperazine, W-7, and W-13
The effects of anticalmodulin agents, namely trifluoperazine (TFP) and two naphthalene sulfonamide derivatives (W-7 and W-13), were tested on the growth of a human breast cancer cell line (MDA-MB-231) using a ...
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Article
Effect of synthetic prostaglandin E1 analog on aspirin-induced gastric bleeding and secretion
Twelve healthy subjects were given aspirin (975 mg four times a day) for four days. On days three and four, each dose of aspirin was preceded by a synthetic protaglandin E1 analog (misoprostol, Searle) either 25 ...
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Article
Idiopathic pancreatitis associated with inflammatory bowel disease
The list of extraintestinal manifestations of inflammatory bowel diseases does not classically include pancreatitis and pancreatic insufficiency. We report here six cases of unexplained pancreatitis associated...
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Article
Effect of ethanol ingestion on postprandial gastric emptying and secretion, biliopancreatic secretions, and duodenal absorption in man
Although abdominal complaints are frequent in both acute and chronic alcoholism, little is known of the effect of ingestion of ethanol with a meal on the function of the upper digestive tract. We have studied ...
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Article
Gastrointestinal motility disorders
A classification of gastrointestinal motility disorders is offered based upon the type of disorder in transit (delay or acceleration), and the region of the gastrointestinal tract affected. Specific abnormalit...
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Chapter
The Role of Promotion in the Carcinogenesis of Nasopharyngeal Carcinoma
It is well known that evidence for the chemical promotion of cocarcinogenesis was first provided by Berenblum. Subsequently, Mottram, Boutwell, Van Duren, and Hecker were responsible for defining many importan...
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Chapter
Vitamin Intervention in Precancerous Lesions of the Esophagus in a High-Risk Population of China
Results of a study are presented which, in the meantime, have been published elsewhere [1]. A brief summary is given below.
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Chapter
Oncogenes in Primary Hepatic Cancer
Primary hepatic cancer (PHC) is one of the most prevalent malignancies on the east and south coasts of China. Extensive epidemiological surveys of PHC in these areas indicate that the incidence of PHC is close...
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Article
Manifestations dyspeptiques: la preuve par Peridys
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Article
Pancreatic exocrine enzymes during the neonatal period in postmature rats
Pancreatic content of exocrine enzymes in newborn rat pups shows a sharp decline soon after birth. To investigate if this decline is a preprogrammed and, therefore, inherently controlled phenomenon, or a resul...
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Article
Potentiation of platinum analogue cytotoxicity by hyperthermia
Carboplatin and iproplatin, two new analogues of cisplatin, appear to have comparable activity in the treatment of advanced ovarian cancer, but minimal nephro- and neurotoxicities. Hyperthermia can potentiate ...
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Article
Symptomatic, radionuclide and therapeutic assessment of chronic idiopathic dyspepsia
Twenty-eight patients with chronic idiopathic dyspepsia defined by the presence of chronic unexplained symptoms suggestive of gastric stasis and directly related to food ingestion were included in this prospec.....
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Chapter
Metabolic and Physiological Responses of Mammary Carcinoma in the Mouse and Normal Brain Tissue in the Rat to Photodynamic Therapy
The therapeutic interaction of light with malignant tissue via a photosensitizer has a long history. As early as 1903, skin cancer was treated with topically applied eosin and sunlight (1). The cytotoxic effec...
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Article
Severe short bowel syndrome with a surgically reversed small bowel segment
We report a case of short bowel syndrome (60 cm of jejunum anastomosed to the left colon) with reversal of the distal 15 cm of jejunum in a 21-year-old man. The nutritional absorptive capacity and digestive mo...
