6,313 Result(s)

Article

Impact of Online Video Game-Based Dichoptic Training on Binocular Vision Rehabilitation in Post-surgical Patients with Intermittent Exotropia

Dichoptic training has emerged as a promising rehabilitation approach for improving binocular visual function in patients with strabismus. A prospective observational study design was employed to assess the ef...

Xuan Qiu, Yusong Zhou, ** Yu, Zhonghao Wang, Tao Shen… in Ophthalmology and Therapy (2024)

Article

Correction: A positive feedback inhibition of isocitrate dehydrogenase 3β on paired-box gene 6 promotes Alzheimer-like pathology

**n Wang, Qian Liu, Hai-tao Yu, Jia-zhao **e… in Signal Transduction and Targeted Therapy (2024)

Article

Evaluation of the clinical efficacy of using an inverted triangular cannulated compression screw in combination with positive or negative buttress reduction for the healing of femoral neck fractures

We aimed to compare the clinical efficacy of inverted triangular cannulated compression screws combined with Gotfried positive or negative buttress reduction in the healing of femoral neck fractures.

Gang Wang, Cui Tang, Yong Tang, Rui Wang, Tugang Shen… in BMC Musculoskeletal Disorders (2024)

Article

SHR-A1811 (antibody-drug conjugate) in advanced HER2-mutant non-small cell lung cancer: a multicenter, open-label, phase 1/2 study

A dose-escalation and expansion, phase 1/2 study (ClinicalTrials.gov, NCT04818333) was conducted to assess the novel antibody-drug conjugate SHR-A1811 in pretreated HER2-altered advanced non-small cell lung ca...

Ziming Li, Zhengbo Song, Wei Hong, Nong Yang… in Signal Transduction and Targeted Therapy (2024)

Article

Targeting CD73 limits tumor progression and enhances anti-tumor activity of anti-PD-1 therapy in intrahepatic cholangiocarcinoma

Patients with intrahepatic cholangiocarcinoma (iCCA) respond poorly to immune checkpoint blockades (ICBs). In this study, we aimed to dissect the potential mechanisms underlying poor response to ICBs and explo...

Bao-Ye Sun, Dai Zhang, Wei Gan, **g-Fang Wu… in Journal of Cancer Research and Clinical On… (2024)

Article

The value of deep learning-based X-ray techniques in detecting and classifying K-L grades of knee osteoarthritis: a systematic review and meta-analysis

Knee osteoarthritis (KOA), a prevalent degenerative joint disease, is primarily diagnosed through X-ray imaging. The Kellgren-Lawrence grading system (K-L) is the gold standard for evaluating KOA severity thro...

Haoming Zhao, Liang Ou, Ziming Zhang, Le Zhang, Ke Liu, Jianjun Kuang in European Radiology (2024)

Article

Woven coronary artery with acquired etiology: the natural history documented by serial angiography and optical coherence tomography

Woven coronary artery (WCA) is a rare anomaly and its etiology remains speculative. Both congenital and acquired factors are considered to be concerned with the pathogenesis. In a 35-year-old man, the tissue c...

Jiannan Li, **aoli Wang, Chen Liu, Peng Zhou, Hanjun Zhao in BMC Cardiovascular Disorders (2024)

Article

Effect of spin-lock frequency on quantitative myocardial T1ρ map**

To use T1ρ map** to assess myocardial fibrosis and to provide a reference for future clinical application, it is necessary to understand the factors influencing T1ρ values. This study explored the influence ...

Caiyun Han, Huimin Xu, Hui Gao, Fang Liu, Jian Wu, Yan Liu… in Insights into Imaging (2024)

Article

Decreased levels of PTCSC3 promote the deterioration of prostate cancer and affect the prognostic outcome of patients through sponge miR-182-5p

Prostate cancer, characterized by its insidious onset and short overall survival, and has seen a rise in incidence over recent decades. This study aims to investigate the expression and molecular mechanism of ...

Lin Cheng, Shuhui Li, Deqi Jiang, Rongkai Sun, Yueshan Wang, Jianchao Zhang… in BMC Urology (2024)

Article

Radiomics predict the WHO/ISUP nuclear grade and survival in clear cell renal cell carcinoma

This study aimed to assess the predictive value of radiomics derived from intratumoral and peritumoral regions and to develop a radiomics nomogram to predict preoperative nuclear grade and overall survival (OS...

**aoxia Li, **glai Lin, Hongliang Qi, Chenchen Dai, Yi Guo… in Insights into Imaging (2024)

Article

Association of resection margin distance with anastomotic recurrence in stage I-III colon cancer: data from the National Colorectal Cancer Cohort (NCRCC) study in China

Few studies have focused on anastomotic recurrence (AR) in colon cancer. This study aimed to clarify the association of resection margin distance with AR and compare the prognosis with nonanastomotic local rec...

Fei Huang, Shan Jiang, Ran Wei, Tixian **ao… in International Journal of Colorectal Disease (2024)

Article

The impact of diet, exercise, and sleep on Helicobacter pylori infection with different occupations: a cross-sectional study

Associations between Helicobacter pylori infection and lifestyle factors vary greatly by geographic location. This study aims to evaluate the prevalence of Helicobacter pylori infection in the Hunan cohort of cen...

Shiwen He, Xue He, Yinglong Duan, Yating Luo, Yuxuan Li, **g Li… in BMC Infectious Diseases (2024)

Article

Central nervous system involvement in chronic lymphocytic leukemia: a case report and review of literature

Central nervous system involvement in chronic lymphocytic leukemia rarely occurs, and there is no standard therapy for central nervous system involvement in chronic lymphocytic leukemia. This article aims to a...

Li-Yuan Qin, Ye Geng, Jian-Feng Mu, Wen-Jun Wang… in Journal of Medical Case Reports (2024)

Article

A separate-dural-incision method of extradural dumbbell spinal schwannoma resection: cumulative experience at a single center

To present our experience in the surgical management of completely extradural dumbbell spinal schwannomas with a new surgical strategy.

Li Jia, Minghui Zeng, Zhiyu **, Lin Wang, Jiang Liu in BMC Surgery (2024)

Article

Efficacy and safety of oral semaglutide vs sitagliptin in a predominantly Chinese population with type 2 diabetes uncontrolled with metformin: PIONEER 12, a double-blind, Phase IIIa, randomised trial

The aim of this study was to assess the efficacy and safety of oral semaglutide vs sitagliptin in a predominantly Chinese population with type 2 diabetes inadequately controlled with metformin treatment.

Linong Ji, Rikke M. Agesen, Stephen C. Bain, Fangming Fu, Sanaz Gabery… in Diabetologia (2024)

Article

Causal inference of the effect of blood proteome on the risk of head and neck cancer: two-sample Mendelian randomization

Early diagnosis of head and neck cancer can improve therapeutic outcomes but remains a challenge. The blood proteome can comprise a key source of biomarkers that enable the early diagnosis and precision medici...

Zhen Wang, Jianhao Wu in Discover Oncology (2024)

Article

Surgical outcomes of major vascular resection for retroperitoneal liposarcoma from a high‑volume sarcoma center: a propensity score matching analysis

Radical resection of retroperitoneal liposarcoma (RLPS) may necessitate vascular resection and reconstruction. The study was conducted to assess surgical outcomes of surgery for RLPS with major vascular involv...

Guoqiang Xue, **aopeng Wang, Bonan Liu… in Journal of Cancer Research and Clinical On… (2024)

Article

Targeting the PI3K/AKT/mTOR pathway offer a promising therapeutic strategy for cholangiocarcinoma patients with high doublecortin-like kinase 1 expression

Cholangiocarcinoma (CCA), characterized by high heterogeneity and extreme malignancy, has a poor prognosis. Doublecortin-like kinase 1 (DCLK1) promotes a variety of malignant cancers in their progression. Targ...

Ziwei Liang, Yang Ge, Jianjian Li… in Journal of Cancer Research and Clinical On… (2024)

Article

Operative treatment of isolated epiphyseal fracture of the distal fibula: 1 case report and literature review

Pediatric ankle injuries are common; ankle epiphyseal fractures are also common in children. But isolated distal epiphyseal fibular fractures of the distal fibula are clinically rare. We describe one unusual c...

Zhongbo Jiang, Liang Yue, Deheng Wang, Yanchen Liang… in BMC Musculoskeletal Disorders (2024)

Article

Effects of the subtypes of apolipoprotein E on immune inhibition and prognosis in patients with Hepatocellular Carcinoma

To investigate whether prognosis of patients with hepatocellular carcinoma (HCC) is affected by the abundance and subgroups of myeloid-derived suppressor cells (MDSCs) as well as subtypes and expression of apo...

Bowen Gao, Peiyun Zhou, Li Wang, Zhutao Wang… in Journal of Cancer Research and Clinical On… (2024)