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37,278 Result(s)
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Article
Intravesical formalin for the control of intractable bladder haemorrhage secondary to radiation cystitis or bladder cancer
During the last two years, 17 patients with haemorrhage due to radiation cystitis or bladder cancer have been treated by intravesical infusion of 10% Formalin solution. The results were very good in 9 cases, s...
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Article
Colonic inhibition of gastric secretion in man
The effect of colonic infusion of various solutions on submaximal pentagastrin-stimulated gastric secretion was determined in healthy volunteers. Hypertonic (823 mOsm/kg) glucose, mannitol, and saline, and als...
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Article
Haemodynamic effects of rhomotoxin on canines
Rhomotoxin is a pharmacologically active principle isolated from the fruits of Rhododendron molle G. Don. Clinical experience demonstrated that it had an antihypertensive effect. In the present work, its haemo...
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Article
Studies on the calcium antagonistic action of tetrandrine: I. Effects of tetrandrine on the isolated guinea pig atrium
Tetrandrine (T), an alkaloid isolated from the root of Stephania tetrandra S. Moore, possessed an antihypertensive, antianginal and antiarrhythmogenic effect.
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Chapter and Conference Paper
Intracranial Hemorrhage and Hematoma Following Open-Heart Surgery
Neurological damage following open heart surgery has been a subject of much concern ever since the employment of cardiopulmonary bypass in cardiac operations. Various lesions including cerebral edema, petechia...
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Article
Studies on the calcium antagonistic action of tetrandrine: II. Effects of tetrandrine on cat papillary muscle
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Tetrandrine was found to decrease the contractility, ±dT/dtmax and automaticity and prolong the functional re...
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Article
Isotope studies in gastric emptying
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Article
Gastric emptying and intragastric distribution of lipids in man
We measured gastric emptying of fat and water from a solid-liquid meal in healthy volunteers using a tubeless scintigraphic method. Selenium-75 glycerol triether, incorporated in butter, was the lipid-phase ma...
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Article
Studies on the calcium antagonistic action of tetrandrine: III. Effect of tetrandrine on positive inotropic action of isoproterenol and Ca++ and on excitation-contraction coupling in isolated cat papillary muscles
The effects of tetrandrine, verapamil, propranolol and practolol on isoproterenol dose-response relationships and influence of tetrandrine, verapamil and nifedipine on calcium dose-response relationships and o...
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Article
The value of S-100 immunostaining as a diagnostic tool in human malignant melanomas
The brain proteins S-100 and neuron-specific enolase have been reported by separate groups to be present in human malignant melanomas. There is no systematic study comparing the occurrence of these proteins in...
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Article
Gastric bleeding and gastric secretion with sulindac and naproxen
We have examined concurrent gastric secretory rates and bleeding by a gastric wash technique during treatment with naproxen, sulindac, and placebo. Twelve subjects, in each of 4 treatment periods, took either ...
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Article
Comparative in vitro antitumor activity of homoharringtonine and harringtonine against clonogenic human tumor cells
Harringtonine and its derivative homoharringtonine are ester-containing anti-leukemic alkaloids isolated from the tree Cephalotaxus harringtonia. In order to compare their antitumor activity against solid tumo...
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Article
An ultrastructural study of degeneration of articular cartilage caused by experimental articular mechanical changes
In the present study 40 mature rabbits were used to cause de-arrangement of the articular surfaces by arthrotomy. The ultrastructural changes of the articular cartilage in the pathological model were studied u...
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Article
Antitumor activity of didemnin B in the human tumor stem cell assay
In vitro studies of the schedule dependency and cytotoxicity of didemnin B, a novel depsipeptide isolated from a Carribean tunicate (Didemnidae), were carried out in fresh tumor cells obtained from biopsies fr...
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Article
Tracing the origin of the sympathetic afferent nerve of the ventriculus cordis by means of horseradish peroxidase method in the rat
Two to five μ1 20–50% horseradish peroxidase (HRP) in normal saline solution have been injected into the myocardium of the left ventricle of 36 rats. HRP positive reaction granules in spinal ganglion cells hav...
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Article
Inhibition of human breast cancer colony formation by anticalmodulin agents: Trifluoperazine, W-7, and W-13
The effects of anticalmodulin agents, namely trifluoperazine (TFP) and two naphthalene sulfonamide derivatives (W-7 and W-13), were tested on the growth of a human breast cancer cell line (MDA-MB-231) using a ...
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Article
Effect of synthetic prostaglandin E1 analog on aspirin-induced gastric bleeding and secretion
Twelve healthy subjects were given aspirin (975 mg four times a day) for four days. On days three and four, each dose of aspirin was preceded by a synthetic protaglandin E1 analog (misoprostol, Searle) either 25 ...
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Article
Effects of rhomotoxin on cat papillary muscle
Clinical experience has demonstrated that rhomotoxin, isolated from the fruits of Rhododendron molle G. Don, has antihypertensive and antiarrhythmic effects. In the present work, its direct actions on cat papi...
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Article
Detection and removal of intracardiac residual air during open heart surgery with CPB under the guidance of echocardiography
Embolism from air retained within the open heart has been recognized as a potential hazard in direct vision intracardiac surgery. To assess whether Mmode echocardiography can accurately detect intracardiac air...
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Article
Studies on the calcium antagonistic action of tetrandrine: IV. Effects of tetrandrine on isoproterenol and calcium-mediated positive chronotropic action in isolated rabbit atria
In isolated spontaneously beating atria of rabbits, tetrandrine (Tet) and verapamil (Ver) shifted the concentration-rate curves to isoproterenol (Iso) to the right in a non-parallel manner and depressed their ...