52 Result(s)
within
Jialing **e
Science, Humanities and Social Sciences, multidisciplinary
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Article
Using laser confocal scanning microscope to study ischemia-hypoxia injury in rat brain slice
The level of lipid peroxidation and cellular necrosis in rat living brain slices during brain ischemia-hypoxia injury have been observed using a laser confocal scanning microscope (LCSM) with double labeling o...
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Article
In-situ Mg77Cu12Zn5Y6 bulk metallic glass matrix composite with extraordinary plasticity
We report experimental evidence of in-situ Mg77Cu12Zn5Y6 bulk metallic glass (BMG) matrix composite with extraordinary plastic strain of 18.5% and specific strength of 4.31×105 N·m·kg−1, which are the highest pla...
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Article
Influence of contaminations on combustion kinetics in hydrogen-fueled engine
In this work, we investigate the combustion of hydrogen fuel through the wind tunnel tests. Two kinds of fuel, the pure hydrogen and the hydrogen-ethene mixture, have been chosen to heat the oxygen-enriched ai...
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Article
Arrangement strategy of ground heat exchanger with groundwater
The orientation strategy of side pipe and the heat transfer performance of six ground heat exchangers (GHEs) were optimized by numerical simulation, with soil being treated as a porous medium. An experiment on...
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Article
Experimental investigation on system with combination of ground-source heat pump and solar collector
This paper presents the heating performance and energy distribution of a system with the combination of ground-source heat pump and solar collector or a solar-assisted ground-source heat pump system (SAGSHPS) ...
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Article
Thermal response test by improved test rig with heating or cooling soil
An improved test rig providing both the heat and cold source was used to perform thermal response test (TRT), and the line source model was used for data analysis. The principle of determining the temperature ...
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Article
How cat lands: insights into contribution of the forelimbs and hindlimbs to attenuating impact force
To safely land after different drops, cats can perfectly use their limbs as dampers to dissipate impact forces. Yet, we know little about the contribution of the forelimbs and hindlimbs of cats to attenuating ...
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Article
Numerical study on heat transfer enhancement for use of corrugated, nodal and horizontal grain tubes
With isopentane as working fluid, the heat transfer performances for corrugated, nodal and horizontal grain tubes are simulated. The structural parameters of the three kinds of tubes are compared with those of...
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Article
Parametric optimization of organic Rankine cycle with R245fa/R601a as working fluid
In order to select the appropriate working fluids and optimize parameters for medium-temperature geothermally-powered organic Rankine cycle (ORC), R245fa is mixed with R601a at geothermal water temperature of ...
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Article
Open AccessInbR, a TetR family regulator, binds with isoniazid and influences multidrug resistance in Mycobacterium bovis BCG
Isoniazid (INH), an anti-tuberculosis (TB) drug, has been widely used for nearly 60 years. However, the pathway through which Mycobacterium tuberculosis responds INH remain largely unclear. In this study, we char...
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Article
Open AccessAstroglial β-Arrestin1-mediated Nuclear Signaling Regulates the Expansion of Neural Precursor Cells in Adult Hippocampus
Adult hippocampal neurogenesis is crucial for preserving normal brain function, but how it is regulated by niche cells is uncertain. Here we show that β-arrestin 1 (β-arr1) in dentate gyrus (DG) regulates neur...
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Article
Open AccessConformational Heterogeneity of Bax Helix 9 Dimer for Apoptotic Pore Formation
Helix α9 of Bax protein can dimerize in the mitochondrial outer membrane (MOM) and lead to apoptotic pores. However, it remains unclear how different conformations of the dimer contribute to the pore formation...
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Article
Open AccessFluid–structure interaction analysis of the drop impact test for helicopter fuel tank
The crashworthiness of helicopter fuel tank is vital to the survivability of the passengers and structures. In order to understand and improve the crashworthiness of the soft fuel tank of helicopter during th...
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Article
Open AccessThe RhoA/ROCK Pathway Ameliorates Adhesion and Inflammatory Infiltration Induced by AGEs in Glomerular Endothelial Cells
A recent study demonstrated that advanced glycation end products (AGEs) play a role in monocyte infiltration in mesangial areas in diabetic nephropathy. The Ras homolog gene family, member A Rho kinase (RhoA/R...
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Article
Open AccessEffects of hydrological regime on development of Carex wet meadows in East Dongting Lake, a Ramsar Wetland for wintering waterbirds
Wet meadows are one of the most important ecological components in floodplain, and are among the most dynamic ecosystems. Understanding the development of wet meadows and contributing environmental factors can...
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Article
Open AccessA data-driven approach for evaluating multi-modal therapy in traumatic brain injury
Combination therapies targeting multiple recovery mechanisms have the potential for additive or synergistic effects, but experimental design and analyses of multimodal therapeutic trials are challenging. To ad...
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Article
Open AccessNuclear localization of Beclin 1 promotes radiation-induced DNA damage repair independent of autophagy
Beclin 1 is a well-established core mammalian autophagy protein that is embryonically indispensable and has been presumed to suppress oncogenesis via an autophagy-mediated mechanism. Here, we show that Beclin ...
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Article
Open AccessQuantitative assessment of liver fibrosis (qFibrosis) reveals precise outcomes in Ishak “stable” patients on anti-HBV therapy
Current widely used semiquantitative histological assessment methods are insensitive to identify subtle changes of liver fibrosis. Therefore, to precisely assess therapeutic efficacy on chronic hepatitis B (CH...
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Article
Open AccessStructure of the herpes simplex virus type 2 C-capsid with capsid-vertex-specific component
Herpes simplex viruses (HSVs) cause human oral and genital ulcer diseases. Patients with HSV-2 have a higher risk of acquiring a human immunodeficiency virus infection. HSV-2 is a member of the α-herpesvirinae su...
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Article
Open AccessEnantioselective Rhodium-Catalyzed Cycloisomerization of 1,6-Allenynes to access 5/6-Fused Bicycle[4.3.0]nonadienes
Transition-metal-catalyzed cycloisomerization of 1,n-allenynes represents a powerful synthetic tool to rapidly assemble complex polycyclic skeletons from simple linear substrates. Nevertheless, there are no re...
