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    Article

    Utilizing a novel model of PANoptosis-related genes for enhanced prognosis and immune status prediction in kidney renal clear cell carcinoma

    Kidney renal clear cell carcinoma (KIRC) is the most common histopathologic type of renal cell carcinoma. PANoptosis, a cell death pathway that involves an interplay between pyroptosis, apoptosis and necroptos...

    Zhansheng Jiang, Jiahe Wang, Chenghuan Dao, Mingyu Zhu, Yuan Li, Fangchao Liu in Apoptosis (2024)

  2. Article

    Open Access

    Hedgehog signaling in tissue homeostasis, cancers, and targeted therapies

    The past decade has seen significant advances in our understanding of Hedgehog (HH) signaling pathway in various biological events. HH signaling pathway exerts its biological effects through a complex signalin...

    Junjun **g, Zhuoxuan Wu, Jiahe Wang in Signal Transduction and Targeted Therapy (2023)

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    Article

    LRRC3B is downregulated in non-small-cell lung cancer and inhibits cancer cell proliferation and invasion

    LRRC3B has emerged as a tumor suppressor in several human cancers. However, its expression pattern and biological roles in human non-small-cell lung cancer (NSCLC) have not been explored. In the present study,...

    Liang Kan, Hui Li, Yi Zhang, Jiahe Wang, Huiyan Niu, Hongfang Jiang in Tumor Biology (2016)

  4. Article

    Erratum to: RNA interference-mediated knockdown of RhoGDI2 induces the migration and invasion of human lung cancer A549 cells via activating the PI3K/Akt pathway

    Huiyan Niu, Baogang Wu, Yang Peng, Hongfang Jiang, Yi Zhang, Jiahe Wang in Tumor Biology (2015)

  5. No Access

    Article

    RNA interference-mediated knockdown of RhoGDI2 induces the migration and invasion of human lung cancer A549 cells via activating the PI3K/Akt pathway

    Rho GDP dissociation inhibitor 2 (RhoGDI2) has been identified as a tumor suppressor gene for cellular migration and invasion. However, the underlying mechanism and effector targets of RhoGDI2 in lung cancer a...

    Huiyan Niu, Baogang Wu, Yang Peng, Hongfang Jiang, Yi Zhang, Jiahe Wang in Tumor Biology (2015)

  6. Article

    Open Access

    Rapamycin potentiates cytotoxicity by docetaxel possibly through downregulation of Survivin in lung cancer cells

    To elucidate whether rapamycin, the inhibitor of mTOR (mammalian target of rapamycin), can potentiate the cytotoxic effect of docetaxel in lung cancer cells and to probe the mechanism underlying such enhancement.

    Huiyan Niu, Jiahe Wang, Hui Li, ** He in Journal of Experimental & Clinical Cancer … (2011)