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    Article

    Identification of Protein–Protein Interaction Associated Functions Based on Gene Ontology

    Protein–protein interactions (PPIs) involve the physical or functional contact between two or more proteins. Generally, proteins that can interact with each other always have special relationships. Some previo...

    Yu-Hang Zhang, FeiMing Huang, JiaBo Li, WenFeng Shen, Lei Chen in The Protein Journal (2024)

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    Open Access

    TCAF2 drives glioma cellular migratory/invasion properties through STAT3 signaling

    Glioma is an intracranial tumor characterized by high mortality and recurrence rates. In the present study, the association of TRPM8 channel-associated factor 2 (TCAF2) in glioma was investigated using bioinfo...

    Debo Yun, Jianshen Liang, Xuya Wang, Jikang Fan in Molecular and Cellular Biochemistry (2023)

  3. Article

    Open Access

    Autophagy suppresses self-renewal ability and tumorigenicity of glioma-initiating cells and promotes Notch1 degradation

    Autophagy is a vital process that involves degradation of long-lived proteins and dysfunctional organelles and contributes to cellular metabolism. Glioma-initiating cells (GICs) have the ability to self-renew,...

    Zhennan Tao, Tao Li, Haiwen Ma, Yihan Yang, Chen Zhang, Long Hai in Cell Death & Disease (2018)

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    Article

    GSA: a GPU-accelerated structure similarity algorithm and its application in progressive virtual screening

    A new algorithm is proposed for accelerating chemical structure similarity search by means of graphic processing unit technology. Experiments demonstrate that the new algorithm is on average more than 120-time...

    **n Yan, Qiong Gu, Feng Lu, Jiabo Li, Jun Xu in Molecular Diversity (2012)