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Article
Influence of transgenic rice expressing a fused Cry1Ab/1Ac protein on frogs in paddy fields
As genetic engineering in plants is increasingly used to control agricultural pests, it is important to determine whether such transgenic plants adversely affect non-target organisms within and around cultivat...
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Article
Open AccessBAG3 promotes stem cell-like phenotype in breast cancer by upregulation of CXCR4 via interaction with its transcript
BAG3 is an evolutionarily conserved co-chaperone expressed at high levels and has a prosurvival role in many tumor types. The current study reported that BAG3 was induced under specific floating culture condit...
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Article
Open AccessThe effect of tetrahedron framed permeable weirs on river bed stability in a mountainous area under clear water conditions
A flexible riverbed protection called tetrahedron framed permeable weirs (TFPW) is proposed to protect riverbeds in mountainous areas from scouring. Under clear water conditions, a series of laboratory flume e...
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Article
Open AccessBAG3 regulates stability of IL-8 mRNA via interplay between HuR and miR-4312 in PDACs
Bcl-2 associated athanogene 3 (BAG3) is highly expressed in pancreatic ductal adenocarcinoma (PDAC), and its high expression appears to be a poor prognostic factor for patients with PDAC. In this study, we sho...
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Article
Open AccessBAG3 promotes autophagy and glutaminolysis via stabilizing glutaminase
Bcl-2 associated athanogene 3 (BAG3) is an important molecule that maintains oncogenic features of cancer cells via diverse mechanisms. One of the important functions assigned to BAG3 is implicated in selectiv...
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Article
Effect of δ Phase on Microstructure and Hardness of Heat-Affected Zone in TIG-Welded GH4169 Superalloy
The GH4169 superalloy with different content of δ-Ni3Nb phase was welded by tungsten inert gas welding. A detailed study of microstructure and hardness of heat-affected zone (HAZ) was performed in both as-welded ...
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Article
Experimental and numerical study on the load and deformation mechanism of a flexible net barrier under debris flow impact
High-strength flexible net barriers have achieved a certain effect in mountainous debris flow prevention, but research on the mechanism of structural stress and deformation is still develo**. This study firs...
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Article
Open AccessTRIM29 inhibits miR-873-5P biogenesis via CYTOR to upregulate fibronectin 1 and promotes invasion of papillary thyroid cancer cells
Papillary thyroid cancer (PTC) is the most common endocrine tumor with an increasing incidence, has a strong propensity for neck lymph node metastasis. Limited treatment options are available for patients with...
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Article
O-GlcNAcylation of TRIM29 and OGT translation forms a feedback loop to promote adaptive response of PDAC cells to glucose deficiency
Glucose not only provides energy for tumor cells, but also provides various biomolecules that are essential for their survival, proliferation and invasion. Therefore, it is of great clinical significance to un...
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Article
Open AccessPromotion of stem cell-like phenotype of lung adenocarcinoma by FAM83A via stabilization of ErbB2
Lung cancer stands as the leading cause of mortality among all types of tumors, with over 40% of cases being lung adenocarcinoma (LUAD). Family with sequence similarity 83 member A (FAM83A) emerges as a notabl...