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  1. Article

    Open Access

    Pancreatic draining lymph nodes (PLNs) serve as a pathogenic hub contributing to the development of type 1 diabetes

    Type 1 diabetes (T1D) is a chronic, progressive autoinflammatory disorder resulting from the breakdown of self-tolerance and unrestrained β cell-reactive immune response. Activation of immune cells is initiate...

    Fei Sun, Chun-Liang Yang, Fa-** Wang, Shan-Jie Rong, Jia-Hui Luo… in Cell & Bioscience (2023)

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  2. Article

    Open Access

    SUMOylation of PDPK1 Is required to maintain glycolysis-dependent CD4 T-cell homeostasis

    The immune system is finely tuned to fight against infections, eradicate neoplasms, and prevent autoimmunity. Protein posttranslational modification (PTM) constitutes a molecular layer of regulation to guarant...

    Fei Sun, Fa-** Wang, He Zhu, Tian-Tian Yue, Chun-Liang Yang… in Cell Death & Disease (2022)

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