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5,605 Result(s)
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Article
Genetic differences in susceptibility of pancreatic β cells to virus-induced diabetes mellitus
INFECTION of certain inbred strains of mice with the M variant of encephalomyocarditis (EMC) virus produces β-cell damage and a diabetes-like syndrome1–4. The development of this syndrome is genetically determine...
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Article
Evidence for a single locus controlling susceptibility to virus-induced diabetes mellitus
THE M-variant of encephalomyocarditis virus (EMC) attacks pancreatic β cells and produces a diabetes-like syndrome in certain inbred strains of mice1,2. Studies based on crosses between strains of mice that devel...
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Article
Induction of diabetes by cumulative environmental insults from viruses and chemicals
Encephalomyocarditis virus (EMC) induces diabetes in certain inbred strains of mice by infecting and destroying pancreatic β cells1,2, the severity of the diabetes depending on the number of β cells destroyed3. I...
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Article
Field evidence for active normal faulting in Tibet
Crustal thickening does not now occur in southern Tibet. Field observations made during the Chinese–French expedition of 1980 support an earlier hypothesis based on a combined analysis of satellite images and ...
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Article
The Tibetan side of the India–Eurasia collision
Results are reported from the 1980 joint French–Chinese field expedition in Tibet. The area covered was from the High Himalaya in the south, to the region of Nagqu ∼250 km north of Yangbajain. Ophiolites in th...
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Article
Long-term complications of virus-induced diabetes mellitus in mice
In man, the early metabolic abnormalities associated with diabetes mellitus are followed by various long-term complications1. The cause of these complications is not clear, but they may be secondary to persistent...
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Article
Lhasa block and bordering sutures— a continuation of a 500-km Moho traverse through Tibet
A north–south wide-angle fan-profile through the Yarlung Zangbo suture, across the Lhasa block and through the Bangong-Nujiang suture shows several significant and sharp changes in crustal thickness. Both sutu...
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Article
Crustal structure and variability of the Himalayan border of Tibet
Reversed critical wide angle reflection profiles of the crust–mantle boundary south of the Yarlung Zangbo suture in Tibet reveal a deep (70 km) Moho extending north from the High Himalayas, whilst to the south...
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Article
Structure and evolution of the Himalaya–Tibet orogenic belt
The 1981 French–Chinese expedition to Tibet focused on the Lhasa block, extending earlier coverage 400 km north of the Tsangpo suture. The Lhasa block stood between 10 and 15° N latitude over most of the Upper...
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Chapter
Application of Expert System to the Operation and Control of Industrial Antibiotic Fermentation Process
The computer has been found to have applications in industrial antibiotic fermentation processes for such tasks as data monitoring and logging, but their advanced usage for plant operation optimization and con...
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Chapter
A Modelling Approach to Trouble Diagnosis by Multilevel Fuzzy Functions and its Application
A modelling approach to trouble diagnosis by multilevel fuzzy functions is developed by using fuzzy set theory, on the basis of historical data and experience on a production process. This is a practicable mod...
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Article
Biosynthesis of the reverse transcriptase of hepatitis B viruses involves de novo translational initiation not ribosomal frameshifting
Retroviruses and many other types of genetic elements replicate by reverse transcription of RNA (for reviews, see refs 1 and 2). Although structurally and biologically very diverse, such elements carry conserv...
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Article
Granulocyte- and granulocyte– macrophage-colony stimulating factors induce human endothelial cells to migrate and proliferate
Granulocyte-colony stimulating factor (G-CSF) and granulocyte-macrophage-colony stimulating factor (GM-CSF) belong to a family of glycoprotidic growth factors required for the survival, growth and differentiat...
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Chapter and Conference Paper
Graft Polymerization of Vinyl Monomers onto Plasma-Modified Fillers
Fillers for polymer composites have been modified with plasma of vinyl monomers. The interfacial chemical bonds between plasma polymer sheath and silica filler have been observed by using XPS. X-ray fluorescen...
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Article
The Ailao Shan/Red River metamorphic belt: Tertiary left-lateral shear between Indochina and South China
The relative importance of thickening and strike-slip extrusion in continental collision is debated. Ductile shear in the Ailao Shan/Diancang Shan metamorphic belt, along the Red River in Yunnan, China, yields...
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Article
Polymerase gene products of hepatitis B viruses are required for genomic RNA packaging as well as for reverse transcription
ALL reactions involving reverse transcription of RNA are segre-gated from the cytosol within a subviral particle or capsid composed of the major capsid protein, the polymerase and the RNA tem-plate1. A key step i...
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Article
Fluorescence ratio imaging of cyclic AMP in single cells
FLUORESCENCEimaging is perhaps the most powerful technique currently available for continuously observing the dynamic intracellular biochemistry of single living cells1. However, fluorescent indicator dyes have b...
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Chapter
A monoclonal antibody (E-9) binds preferentially to the vasculatures of human tumors, embryonic and regenerating tissues
Angiogenesis plays an important role in a variety of physiological and pathological processes such as embryogenesis, wound healing and tumour growth. Although vascular smooth muscle cells and pericytes take pa...
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Chapter
Oxygen Free Radicals in the Pathophysiology of Myocardial Ischemia/Reperfusion
In the setting of an acute myocardial infarction, there is a limited time window after the onset of coronary artery occlusion after which reperfusion is associated with irreversible cardiac injury. Cellular mo...
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Article
Functional expression of a rapidly inactivating neuronal calcium channel
DIVERSE types of calcium channels in vertebrate neurons are important in linking electrical activity to transmitter release, gene expression and modulation of membrane excitability1. Four classes of Ca2+ channels...