28 Result(s)
within
Jeong-Han Lee
English
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Article
Open AccessThe Piezo channel is a mechano-sensitive complex component in the mammalian inner ear hair cell
The inner ear is the hub where hair cells (HCs) transduce sound, gravity, and head acceleration stimuli to the brain. Hearing and balance rely on mechanosensation, the fastest sensory signals transmitted to th...
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Article
Predictive factors for conversion from conservatively to surgically treatment osteoporotic thoracolumbar compression fractures based on sagittal parameters and magnetic resonance imaging features
To investigate the relationship between sagittal plane characteristics of the spinal column and conservative treatment failure in acute osteoporotic spinal fractures (OSFs).
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Article
Open AccessRapid Consolidation of WC-ZrSiO4 Hard Materials by Spark Plasma Sintering: Microstructure, Densification, and Mechanical Properties
Densely consolidated WC-based hard materials with 5–20 vol% ZrSiO4 was fabricated by spark plasma sintering at 1400 ℃ at a constant heating rate of 70 ℃/min−1. To achieve mechanical alloying of WC-ZrSiO4, planeta...
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Article
Study on Microstructure and Mechanical Properties of the Al–25Cr–5Si (at%) Alloy Powder Using Gas-Atomization and SPS Process
In order to investigate the microstructure and mechanical properties on Al–25Cr–5Si (at%) alloy, a mixed powder with pure elements and an alloy powder using a gas atomization process were used. Fine and high p...
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Article
Effect of Mechanical Alloying on the Microstructural Evolution of Al60Cr30Si10 Alloys Processed by Spark Plasma Sintering
In this study, Al, Cr and Si fine powders were alloyed by planetary ball milling to investigate their microstructural evolution, following their mechanical alloying behavior. The formation of Al(Cr) supersatur...
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Article
Influence of Phase Composition in TiAlSiN Hard Coatings on the Evolution of Structure and Mechanical Properties
The aim of this study is to investigate the structural evolution and mechanical properties of TiAlSiN coatings when processed by the arc ion plating method. To form a hard coating, Ti, Al, and Si powders were ...
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Article
Open AccessEarly functional alterations in membrane properties and neuronal degeneration are hallmarks of progressive hearing loss in NOD mice
Presbycusis or age-related hearing loss (ARHL) is the most common sensory deficit in the human population. A substantial component of the etiology stems from pathological changes in sensory and non-sensory cel...
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Article
Open AccessSodium-activated potassium channels shape peripheral auditory function and activity of the primary auditory neurons in mice
Potassium (K+) channels shape the response properties of neurons. Although enormous progress has been made to characterize K+ channels in the primary auditory neurons, the molecular identities of many of these ch...
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Article
Characterization and Property Evaluation of Ti-Based Target Materials and Their Nitride Nano-composites Coating Layers
This study formed a hard TiAlSiWN coating layer using Ti, Al, Si and W raw powders that were mechanically alloyed and refined. The TiAlSi and TiAlSiW coating targets were fabricated using a pulse current activ...
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Article
Interaction of acoustic surface waves induced by inter-digital transducer with wall thinning defect in pipe structure
Most structural health monitoring (SHM) systems require transducers permanently attached to or integrated with the monitored structure to form a type of smart structure. It is difficult to permanently attach t...
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Article
Open AccessCoupling of SK channels, L-type Ca2+ channels, and ryanodine receptors in cardiomyocytes
Small-conductance Ca2+-activated K+ (SK) channels regulate the excitability of cardiomyocytes by integrating intracellular Ca2+ and membrane potentials on a beat-to-beat basis. The inextricable interplay between ...
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Article
Plate bending wave propagation behavior under metal sphere impact loading
A loose part can cause component damages and material wear on nuclear power plants; thus, a mass estimation of the loose part is crucial to safety management. A bending wave propagation of a structure under th...
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Article
Osseointegration of magnesium-incorporated sand-blasted acid-etched implant in the dog mandible: Resonance frequency measurements and histomorphometric analysis
The aim of this pilot study was to investigate the bone responses of novel magnesium (Mg)–incorporated sand-blasted and acid-etched (SLA) titanium (Ti) implant in an experimental animal model. Novel Mg-incorpo...
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Protocol
In Vitro Functional Assessment of Adult Spiral Ganglion Neurons (SGNs)
Spiral ganglion neurons (SGNs) faithfully encode acoustic waves from hair cells to the cochlear nucleus (CN) using voltage-dependent ion channels. A sizable portion of our knowledge on SGN functions have been ...
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Article
Contact burn due to a heated-wire breathing circuit
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Article
Real time traversability analysis to enhance rough terrain navigation for an 6 × 6 autonomous vehicle
An autonomous vehicle should be driven at a velocity that allows it to feasibly track a predetermined path. For autonomous vehicles that require high velocity navigation over rough terrain, the driving velocit...
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Article
The Qweak: Precision Measurement of the Proton’s Weak Charge by Parity Violating Experiment
The Qweak experiment at the Thomas Jefferson National Accelerator Facility measures the parity violating asymmetry in longitudinally polarized electron scattering from the proton at very low momentum transfer, Q ...
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Article
Open AccessDifferent uptake of gentamicin through TRPV1 and TRPV4 channels determines cochlear hair cell vulnerability
Hair cells at the base of the cochlea appear to be more susceptible to damage by the aminoglycoside gentamicin than those at the apex. However, the mechanism of base-to-apex gradient ototoxicity by gentamicin ...
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Article
Lung injury induced by the pulmonary instillation of povidone-iodine in rats
Povidone-iodine (polyvinylpyrrolidone iodine, PI), which is commonly used as a pre- and postoperative oral antiseptic, has been reported to cause pneumonia secondary to its pulmonary aspiration. Because no stu...
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Article
Cisplatin ototoxicity involves cytokines and STAT6 signaling network
We herein investigated the role of the STAT signaling cascade in the production of pro-inflammatory cytokines and cisplatin ototoxicity. A significant hearing impairment caused by cisplatin injection was obser...
