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    Article

    Catalytic Immunoglobulin Gene Delivery in a Mouse Model of Alzheimer’s Disease: Prophylactic and Therapeutic Applications

    Accumulation of amyloid beta-peptide (Aβ) in the brain is hypothesized to be a causal event leading to dementia in Alzheimer’s disease (AD). Aβ vaccination removes Aβ deposits from the brain. Aβ immunotherapy,...

    **ghong Kou, Junling Yang, Jeong-Eun Lim, Abhinandan Pattanayak… in Molecular Neurobiology (2015)

  2. Article

    Open Access

    TLR4 mutation reduces microglial activation, increases Aβ deposits and exacerbates cognitive deficits in a mouse model of Alzheimer's disease

    Amyloid plaques, a pathological hallmark of Alzheimer's disease (AD), are accompanied by activated microglia. The role of activated microglia in the pathogenesis of AD remains controversial: either clearing Aβ...

    Min Song, **gJi **, Jeong-Eun Lim, **ghong Kou… in Journal of Neuroinflammation (2011)

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