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  1. Article

    Open Access

    Skewness of X-chromosome inactivation increases with age and varies across birth cohorts in elderly Danish women

    Mosaicism in blood varies with age, and cross-sectional studies indicate that for women, skewness of X-chromosomal mosaicism increases with age. This pattern could, however, also be due to less X-inactivation ...

    Jonas Mengel-From, Rune Lindahl-Jacobsen, Marianne Nygaard in Scientific Reports (2021)

  2. Article

    Open Access

    DNA hypermethylation and differential gene expression associated with Klinefelter syndrome

    Klinefelter syndrome (KS) has a prevalence ranging from 85 to 250 per 100.000 newborn boys making it the most frequent sex chromosome aneuploidy in the general population. The molecular basis for the phenotypi...

    Anne Skakkebæk, Morten Muhlig Nielsen, Christian Trolle, Søren Vang in Scientific Reports (2018)