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    Book

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    Chapter

    Summary and Conclusions

    Life is only possible because the genomic information in a cell’s chromosomes is copied from one generation to the next, by means of DNA replication.

    Jens Karschau in Mathematical Modelling of Chromosome Replication and Replicative Stress (2015)

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    Chapter

    Introduction

    To accomplish their numerous tasks cells must create and control an internal (spatial and temporal) order of processes by properly organising their resources. One of these processes—arguably the most crucial p...

    Jens Karschau in Mathematical Modelling of Chromosome Replication and Replicative Stress (2015)

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    Chapter

    Actively Replicating Domains Randomly Associate into Replication Factories

    In the previous chapter DNA was treated as a stiff, one-dimensional line. However within a cellular environment DNA diffuses and organises into structures on different scales as for instance being wrapped arou...

    Jens Karschau in Mathematical Modelling of Chromosome Replication and Replicative Stress (2015)

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    Chapter

    Optimal Origin Placement for Minimal Replication Time

    Eukaryotic genomes vary in their size and are much larger than their bacterial counterpart, e.g. that of Saccharomyces cerevisiae is \({\sim }\) ...

    Jens Karschau in Mathematical Modelling of Chromosome Replication and Replicative Stress (2015)

  6. Article

    Open Access

    Renormalization group theory for percolation in time-varying networks

    Motivated by multi-hop communication in unreliable wireless networks, we present a percolation theory for time-varying networks. We develop a renormalization group theory for a prototypical network on a regula...

    Jens Karschau, Marco Zimmerling, Benjamin M. Friedrich in Scientific Reports (2018)

  7. Article

    Open Access

    Mathematical model for the thermal enhancement of radiation response: thermodynamic approach

    Radiotherapy can effectively kill malignant cells, but the doses required to cure cancer patients may inflict severe collateral damage to adjacent healthy tissues. Recent technological advances in the clinical...

    Adriana M. De Mendoza, Soňa Michlíková, Johann Berger, Jens Karschau in Scientific Reports (2021)

  8. Article

    Open Access

    Effectiveness of extended shutdown measures during the ´Bundesnotbremse´ introduced in the third SARS-CoV-2 wave in Germany

    A third SARS-CoV-2 infection wave has affected Germany from March 2021 until April 24th, until the ´Bundesnotbremse´ introduced nationwide shutdown measures. The ´Bundesnotbremse´ is the technical term which w...

    Andreas Schuppert, Katja Polotzek, Jens Karschau, Christian Karagiannidis in Infection (2021)