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Open AccessBacterial extracellular vesicles repress the vascular protective factor RNase1 in human lung endothelial cells
Sepsis is one of the leading causes of death worldwide and characterized by blood stream infections associated with a dysregulated host response and endothelial cell (EC) dysfunction. Ribonuclease 1 (RNase1) a...
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Article
Open AccessBacterial vesicles block viral replication in macrophages via TLR4-TRIF-axis
Gram-negative bacteria naturally secrete nano-sized outer membrane vesicles (OMVs), which are important mediators of communication and pathogenesis. OMV uptake by host cells activates TLR signalling via transp...