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  1. Article

    Open Access

    Acute kidney injury is a powerful independent predictor of mortality in critically ill patients: a multicenter prospective cohort study from Kinshasa, the Democratic Republic of Congo

    Despite the growing incidence of acute kidney injury (AKI) worldwide, there is little data on the burden and outcomes of AKI in intensive care unit (ICU) in low resource settings. The present study assessed th...

    Angèle Masewu, Jean-Robert Makulo, François Lepira, Eric Bibonge Amisi in BMC Nephrology (2016)

  2. Article

    Open Access

    Albuminuria, serum antioxidant enzyme levels and markers of hemolysis and inflammation in steady state children with sickle cell anemia

    Oxidative stress is thought to be involved in the pathogenesis of microalbuminuria in Sickle cell anemia (SCA). Antioxidant enzymes such as glutathione peroxidase (GPx) and Cu-Zn superoxide dismutase (SOD) may...

    Karen E. Itokua, Jean Robert Makulo, François B. Lepira, Michel N. Aloni in BMC Nephrology (2016)

  3. Article

    Open Access

    Reverse epidemiology of elevated blood pressure among chronic hemodialysis black patients with stroke: a historical cohort study

    Stroke is the third leading cause of cardiovascular mortality in dialysis patients. The objective of this study was to assess the extent of stroke in chronic hemodialysis patients.

    Yannick Nlandu, François Lepira, Jean-Robert Makulo, Yannick Engole in BMC Nephrology (2017)