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  1. Article

    Open Access

    SARS-CoV2 infection in symptomatic patients: interest of serological tests and predictors of mortality: experience of DR Congo

    In symptomatic patients, the diagnostic approach of COVID-19 should be holistic. We aimed to evaluate the concordance between RT-PCR and serological tests (IgM/IgG), and identify the factors that best predict ...

    Jean-Robert Makulo, Madone Ndona Mandina in BMC Infectious Diseases (2022)

  2. Article

    Open Access

    Prevalence and associated factors of subclinical atherosclerosis in rheumatoid arthritis at the university hospital of Kinshasa

    Rheumatoid arthritis (RA) is associated with a 5 to 10 years reduction in life expectancy due to premature atherosclerosis. This reduction is the consequence of traditional cardiovascular risk factors (TCRF) a...

    Christophe Mulumba, Pierrot Lebughe, Jean-Marie Mbuyi-Muamba in BMC Rheumatology (2019)

  3. Article

    Open Access

    Magnitude of elevated iron stores and risk associated in steady state sickle cell anemia Congolese children: a cross sectional study

    The serum ferritin assay is recommended in Sickle Cell Anemia (SCA) patients receiving regular transfusions. According to several authors, elevated iron stores indicating iron chelation corresponds to hyperfer...

    Jean-Robert Makulo, Karen Efombola Itokua, Rosette Kevani Lepira in BMC Hematology (2019)

  4. Article

    Open Access

    Reverse epidemiology of elevated blood pressure among chronic hemodialysis black patients with stroke: a historical cohort study

    Stroke is the third leading cause of cardiovascular mortality in dialysis patients. The objective of this study was to assess the extent of stroke in chronic hemodialysis patients.

    Yannick Nlandu, François Lepira, Jean-Robert Makulo, Yannick Engole in BMC Nephrology (2017)

  5. Article

    Open Access

    Albuminuria, serum antioxidant enzyme levels and markers of hemolysis and inflammation in steady state children with sickle cell anemia

    Oxidative stress is thought to be involved in the pathogenesis of microalbuminuria in Sickle cell anemia (SCA). Antioxidant enzymes such as glutathione peroxidase (GPx) and Cu-Zn superoxide dismutase (SOD) may...

    Karen E. Itokua, Jean Robert Makulo, François B. Lepira, Michel N. Aloni in BMC Nephrology (2016)

  6. Article

    Open Access

    Acute kidney injury is a powerful independent predictor of mortality in critically ill patients: a multicenter prospective cohort study from Kinshasa, the Democratic Republic of Congo

    Despite the growing incidence of acute kidney injury (AKI) worldwide, there is little data on the burden and outcomes of AKI in intensive care unit (ICU) in low resource settings. The present study assessed th...

    Angèle Masewu, Jean-Robert Makulo, François Lepira, Eric Bibonge Amisi in BMC Nephrology (2016)