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    Article

    Disturbance of Metabotropic Glutamate Receptor-Mediated Long-Term Depression (mGlu-LTD) of Excitatory Synaptic Transmission in the Rat Hippocampus After Prenatal Immune Challenge

    Maternal immune challenge has proved to induce moderate to severe behavioral disabilities in the offspring. Cognitive/behavioral deficits are supported by changes in synaptic plasticity in different brain area...

    Mélanie Cavalier, Azza Ben Sedrine, Lea Thevenet, Nadine Crouzin… in Neurochemical Research (2019)

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    Article

    Synthesis of C5-tetrazole derivatives of 2-amino-adipic acid displaying NMDA glutamate receptor antagonism

    Five derivatives of 2-amino-adipic acid bearing a tetrazole-substituted in C5 position were synthesized. These compounds displayed selective antagonism towards N-methyl-d-aspartate (NMDA) receptors compared with ...

    Fatimazohra Lenda, Nadine Crouzin, Mélanie Cavalier, Janique Guiramand… in Amino Acids (2011)

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    Chapter

    Excitatory Amino Acid Receptors and Phosphoinositide Breakdown: Facts and Perspectives

    Although phosphoinositides were isolated from brain membranes by Folch in 1949, stimulated phosphoinositide metabolism by neuroactive substances was discovered in 1953 by Hokin and Hokin, who showed that the i...

    Max Récasens, Ebrahim Mayat, Janique Guiramand in Current Aspects of the Neurosciences (1991)