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Article
Open AccessLack of evidence of WNT3A as a candidate gene for congenital vertebral malformations
Prior investigations have not identified a major locus for vertebral malformations, providing evidence that there is genetic heterogeneity for this condition. WNT3A has recently been identified as a negative regu...
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Article
Open AccessPathway analysis of genome-wide data improves warfarin dose prediction
Many genome-wide association studies focus on associating single loci with target phenotypes. However, in the setting of rare variation, accumulating sufficient samples to assess these associations can be diff...