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Article
Open AccessMagnetic excitations in strained infinite-layer nickelate PrNiO2 films
Strongly correlated materials respond sensitively to external perturbations such as strain, pressure, and do**. In the recently discovered superconducting infinite-layer nickelates, the superconducting trans...
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Article
Open AccessComparison of the efficacy and safety of SCD411 and reference aflibercept in patients with neovascular age-related macular degeneration
To compare the efficacy and safety of the proposed aflibercept biosimilar SCD411 and reference aflibercept in patients with neovascular age-related macular degeneration, this randomized, double-masked, paralle...
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Article
Open AccessDigital symbol-digit modalities test with modified flexible protocols in patients with CNS demyelinating diseases
Cognitive impairment (CI) is prevalent in central nervous system demyelinating diseases, such as multiple sclerosis (MS) and neuromyelitis optica spectrum disorders (NMOSD). We developed a novel tablet-based m...
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Open AccessExamining spatiotemporal crowdsensing and caching for population-dynamic OTT content delivery
This study proposes a novel spatiotemporal crowdsensing and caching (SCAC) framework to address the surging demands of urban wireless network traffic. In the context of rampant urbanization and ubiquitous digi...
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Open AccessUtilising Endogenous Biomarkers in Drug Development to Streamline the Assessment of Drug–Drug Interactions Mediated by Renal Transporters: A Pharmaceutical Industry Perspective
The renal secretion of many drugs is facilitated by membrane transporters, including organic cation transporter 2, multidrug and toxin extrusion protein 1/2-K and organic anion transporters 1 and 3. Inhibition...
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Open AccessInterstitial Lung Disease and Progressive Pulmonary Fibrosis: a World Trade Center Cohort 20-Year Longitudinal Study
World Trade Center (WTC) exposure is associated with obstructive airway diseases and sarcoidosis. There is limited research regarding the incidence and progression of non-sarcoidosis interstitial lung diseases...
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Article
Open AccessMyrosinase isogenes in wasabi (Wasabia japonica Matsum) and their putative roles in glucosinolate metabolism
Wasabi, a Brassicaceae member, is well-known for its unique pungent and hot flavor which is produced from glucosinolate (GSL) degradation. Myrosinase (MYR) is a principle enzyme catalyzing the primary conversi...
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Article
Open AccessThe complete chloroplast genome and phylogentic results support the species position of Swertia banzragczii and Swertia marginata (Gentianaceae) in Mongolia
Swertia banzragczii and S. marginata are important medicinal species in Mongolia. However, their taxonomic positions and genetic backgrounds remain unknown. In this study, we explored the complete chloroplast gen...
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Open AccessAn ancestral SARS-CoV-2 vaccine induces anti-Omicron variants antibodies by hypermutation
The immune escape of Omicron variants significantly subsides by the third dose of an mRNA vaccine. However, it is unclear how Omicron variant-neutralizing antibodies develop under repeated vaccination. We anal...
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Open AccessAnalysis of REST binding sites with canonical and non-canonical motifs in human cell lines
Repressor element 1 (RE1) silencing transcription factor (REST) is a transcriptional repressor abundantly expressed in aging human brains. It is known to regulate genes associated with oxidative stress, inflam...
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Article
Open AccessOutcomes of epiretinal proliferation embedding technique in the surgery for full-thickness macular hole
To compare visual and anatomical outcomes between peeling and embedding of epiretinal proliferation in patients with full-thickness macular holes (FTMH) with epiretinal proliferation (EP), this retrospective c...
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Article
Open AccessComparative outcomes and prognostic indicators in adrenalectomy for adrenal metastasis
The indications for adrenalectomy and feasibility of laparoscopic adrenalectomy for adrenal metastasis are controversial. This study aimed to compare the surgical outcomes between open adrenalectomy (OA) and l...
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Open AccessDifferentiation, maturation, and collection of THP-1-derived dendritic cells based on a PEG hydrogel culture platform
Dendritic cell (DC) is a spearhead responsible for immune response and surrounded by extracellular matrix in three-dimensional (3D) tissue. Nevertheless, conventional DC culture has relied on suspension or two...
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Article
Open AccessTorsion and clinical features in patients with acquired fourth cranial nerve palsy
This retrospective study aimed to compare objective/subjective torsion and other clinical characteristics of patients with acquired trochlear nerve palsy. This study included 82 consecutive patients who were d...
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Article
Open AccessComparative plastome analysis and taxonomic classification of snow lotus species (Saussurea, Asteraceae) in Central Asia and Southern Siberia
Four species of Saussurea, namely S. involucrata, S. orgaadayi, S. bogedaensis, and S. dorogostaiskii, are known as the “snow lotus,” which are used as traditional medicines in China (**njiang), Kyrgyzstan, Mongo...
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Article
Open AccessOrthogonal inducible control of Cas13 circuits enables programmable RNA regulation in mammalian cells
RNA plays an indispensable role in mammalian cell functions. Cas13, a class of RNA-guided ribonuclease, is a flexible tool for modifying and regulating coding and non-coding RNAs, with enormous potential for c...
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Article
Open AccessAccelerating materials language processing with large language models
Materials language processing (MLP) can facilitate materials science research by automating the extraction of structured data from research papers. Despite the existence of deep learning models for MLP tasks, ...
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Article
Open AccessDual-targeted nano-encapsulation of neonatal porcine islet-like cell clusters with triiodothyronine-loaded bifunctional polymersomes
There is growing evidence that neonatal porcine islet-like cell clusters (NPCCs) isolated from piglets can be used to treat type 1 diabetes in humans. However, graft rejection is a common complication in human...
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Article
Open AccessWeak signal extraction enabled by deep neural network denoising of diffraction data
The removal or cancellation of noise has wide-spread applications in imaging and acoustics. In applications in everyday life, such as image restoration, denoising may even include generative aspects, which are...
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Open AccessA 6-month exercise intervention clinical trial in women: effects of physical activity on multi-omics biomarkers and health during the first wave of COVID-19 in Korea
Coronavirus disease 2019 (COVID-19) was first reported in December 2019 and the first case in Korea was confirmed on January 20, 2020. Due to the absence of therapeutic agents and vaccines, the Korean governme...
