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A newly developed capture-based sequencing panel for genomic assay of lung cancer

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  1. Article

    Open Access

    Comparative plastome analysis and taxonomic classification of snow lotus species (Saussurea, Asteraceae) in Central Asia and Southern Siberia

    Four species of Saussurea, namely S. involucrata, S. orgaadayi, S. bogedaensis, and S. dorogostaiskii, are known as the “snow lotus,” which are used as traditional medicines in China (**njiang), Kyrgyzstan, Mongo...

    Nudkhuu Nyamgerel, Shukherdorj Baasanmunkh in Functional & Integrative Genomics (2024)

  2. Article

    Open Access

    DDM1-mediated gene body DNA methylation is associated with inducible activation of defense-related genes in Arabidopsis

    Plants memorize previous pathogen attacks and are “primed” to produce a faster and stronger defense response, which is critical for defense against pathogens. In plants, cytosines in transposons and gene bodie...

    Seungchul Lee, Jaemyung Choi, Jihwan Park, Chang Pyo Hong, Daeseok Choi in Genome Biology (2023)

  3. Article

    Open Access

    Whole-genome analysis reveals the contribution of non-coding de novo transposon insertions to autism spectrum disorder

    Retrotransposons have been implicated as causes of Mendelian disease, but their role in autism spectrum disorder (ASD) has not been systematically defined, because they are only called with adequate sensitivit...

    Rebeca Borges-Monroy, Chong Chu, Caroline Dias, Jaejoon Choi, Soohyun Lee in Mobile DNA (2021)

  4. Article

    Open Access

    Genomic approaches to trace the history of human brain evolution with an emerging opportunity for transposon profiling of ancient humans

    Transposable elements (TEs) significantly contribute to sha** the diversity of the human genome, and lines of evidence suggest TEs as one of driving forces of human brain evolution. Existing computational ap...

    Yilan Wang, Boxun Zhao, Jaejoon Choi, Eunjung Alice Lee in Mobile DNA (2021)

  5. Article

    Open Access

    Development of genome engineering technologies in cattle: from random to specific

    The production of transgenic farm animals (e.g., cattle) via genome engineering for the gain or loss of gene functions is an important undertaking. In the initial stages of genome engineering, DNA micro-inject...

    Soo-Young Yum, Ki-Young Youn, Woo-Jae Choi in Journal of Animal Science and Biotechnology (2018)

  6. Article

    Open Access

    funRNA: a fungi-centered genomics platform for genes encoding key components of RNAi

    RNA interference (RNAi) is involved in genome defense as well as diverse cellular, developmental, and physiological processes. Key components of RNAi are Argonaute, Dicer, and RNA-dependent RNA polymerase (RdR...

    Jaeyoung Choi, Ki-Tae Kim, Jongbum Jeon, Jiayao Wu, Hyeunjeong Song in BMC Genomics (2014)

  7. Article

    Open Access

    Genome sequence of the hot pepper provides insights into the evolution of pungency in Capsicum species

    Doil Choi and colleagues report the genome sequence of the hot pepper, Capsicum annuum, as well as the resequencing of two cultivated peppers and a wild species, Capsicum chinense. Comparative genomic analysis ac...

    Seungill Kim, Minkyu Park, Seon-In Yeom, Yong-Min Kim, Je Min Lee in Nature Genetics (2014)

  8. Article

    Open Access

    Fungal plant cell wall-degrading enzyme database: a platform for comparative and evolutionary genomics in fungi and Oomycetes

    Plant cell wall-degrading enzymes (PCWDEs) play significant roles throughout the fungal life including acquisition of nutrients and decomposition of plant cell walls. In addition, many of PCWDEs are also utili...

    Jaeyoung Choi, Ki-Tae Kim, Jongbum Jeon, Yong-Hwan Lee in BMC Genomics (2013)

  9. Article

    Open Access

    Systematic and searchable classification of cytochrome P450 proteins encoded by fungal and oomycete genomes

    Cytochrome P450 proteins (CYPs) play diverse and pivotal roles in fungal metabolism and adaptation to specific ecological niches. Fungal genomes encode extremely variable “CYPomes” ranging from one to more tha...

    Venkatesh Moktali, Jongsun Park, Natalie D Fedorova-Abrams, Bongsoo Park in BMC Genomics (2012)

  10. Article

    Open Access

    Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses

    Richard O'Connell and colleagues report the genomes and transcriptomes of two Colletotrichum plant fungal pathogens. C. higginsianum infects Arabidopsis thaliana, and C. graminicola infects maize (Zea mays); comp...

    Richard J O'Connell, Michael R Thon, Stéphane Hacquard, Stefan G Amyotte in Nature Genetics (2012)

  11. Article

    Open Access

    Variation in chromosome copy number influences the virulence of Cryptococcus neoformans and occurs in isolates from AIDS patients

    The adaptation of pathogenic fungi to the host environment via large-scale genomic changes is a poorly characterized phenomenon. Cryptococcus neoformans is the leading cause of fungal meningoencephalitis in HIV/A...

    Guanggan Hu, Joyce Wang, Jaehyuk Choi, Won Hee Jung, Iris Liu in BMC Genomics (2011)

  12. Article

    Open Access

    Fungal Secretome Database: Integrated platform for annotation of fungal secretomes

    Fungi secrete various proteins that have diverse functions. Prediction of secretory proteins using only one program is unsatisfactory. To enhance prediction accuracy, we constructed Fungal Secretome Database (...

    Jaeyoung Choi, Jongsun Park, Donghan Kim, Kyongyong Jung, Seogchan Kang in BMC Genomics (2010)

  13. Article

    Open Access

    IMGD: an integrated platform supporting comparative genomics and phylogenetics of insect mitochondrial genomes

    Sequences and organization of the mitochondrial genome have been used as markers to investigate evolutionary history and relationships in many taxonomic groups. The rapidly increasing mitochondrial genome sequ...

    Wonhoon Lee, Jongsun Park, Jaeyoung Choi, Kyongyong Jung, Bongsoo Park in BMC Genomics (2009)

  14. Article

    Open Access

    SNUGB: a versatile genome browser supporting comparative and functional fungal genomics

    Since the full genome sequences of Saccharomyces cerevisiae were released in 1996, genome sequences of over 90 fungal species have become publicly available. The heterogeneous formats of genome sequences archived...

    Kyongyong Jung, Jongsun Park, Jaeyoung Choi, Bongsoo Park, Seungill Kim in BMC Genomics (2008)

  15. Article

    Open Access

    Fungal cytochrome P450 database

    Cytochrome P450 enzymes play critical roles in fungal biology and ecology. To support studies on the roles and evolution of cytochrome P450 enzymes in fungi based on rapidly accumulating genome sequences from ...

    Jongsun Park, Seungmin Lee, Jaeyoung Choi, Kyohun Ahn, Bongsoo Park in BMC Genomics (2008)