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  1. No Access

    Article

    Enhanced l-lysine production in threonine-limited continuous culture of Corynebacterium glutamicum by using gluconate as a secondary carbon source with glucose

    In order to improve the production rate of l-lysine, a mutant of Corynebacterium glutamicum ATCC 21513 was cultivated in complex medium with gluconate and glucose as mixed carbon sources. In a batch culture, thi...

    H.-W. Lee, J.-G. Pan, J.-M. Lebeault in Applied Microbiology and Biotechnology (1998)

  2. No Access

    Article

    Characterisation of kinetic parameters and metabolic transition of Corynebacterium glutamicum on l-lysine production in continuous culture

    Kinetic parameters and physiological states of Corynebacterium glutamicum at the growing and l-lysine-overproducing phase were characterised in continuous culture on threonine-limited complex and minimal media. H...

    H.-W. Lee, J.-G. Pan, J.-M. Lebeault in Applied Microbiology and Biotechnology (1995)

  3. No Access

    Article

    Physiological aspects of l-lysine production: effect of nutritional limitations on a producing strain of Corynebacterium glutamicum

    The effect of nutritional limitations, such as phosphorus and carbon, on the production of l-lysine by Corynebacterium glutamicum was studied in continuous culture. We observed that phosphate-limited cultures at ...

    N. Coello, J. G. Pan, J. M. Lebeault in Applied Microbiology and Biotechnology (1992)

  4. No Access

    Article

    Corynebacterium glutamicum: morphological and ultrastructural changes of l-lysine producing cells in continuous culture

    Corynebacterium glutamicum was observed to undergo several morphological and ultrastructural changes during a shift in dilution rate when grown in phosphate-limiting continuous culture. At 0.1 h−1 the cell cultu...

    N. Coello, J. G. Pan, J. M. Lebeault in Applied Microbiology and Biotechnology (1992)