21 Result(s)

Article

The Aurora of March 30

I VENTURE to supplement the reference in NATURE to the Aurora of March 30, by a brief account of an observation made by me at Bristol.

J. RYAN in Nature (1894)

Article

Informatic selection of a neural crest-melanocyte cDNA set for microarray analysis

S. Loftus, Y. Chen, G. Gooden, J. Ryan, G. Birznieks, M. Hilliard… in Nature Genetics (1999)

Chapter and Conference Paper

Adaptive Mesh Refinement and Domain Decomposition: A Framework to Study Multi-physical and Multi-scale Phenomena. First Application to Reacting Gas Flows

The aim of this work is to extend the Adaptive Mesh Refinement (AMR) technique. AMR is an ideal platform for coupling different discretisations and models, as each grid level can use a different solver. Compac...

J. Ryan in Computational Science – ICCS 2006 (2006)

Article

BIM and other BCL-2 family proteins exhibit cross-species conservation of function between zebrafish and mammals

Here we investigate the function of zebrafish Bcl-2 family proteins and demonstrate important conservation of function across zebrafish and mammalian systems. We have isolated a zebrafish ortholog of mammalian BI...

C A Jette, A M Flanagan, J Ryan, U J Pyati, S Carbonneau… in Cell Death & Differentiation (2008)

Article

Erratum: MicroRNA-204 increases sensitivity of neuroblastoma cells to cisplatin and is associated with a favourable clinical outcome

Correction to: British Journal of Cancer (2012) 107, 967–976. doi:10.1038/bjc.2012.356 Upon publication online and in print, the authors realised that a contributor to the original data for this manuscript had...

J Ryan, A Tivnan, J Fay, K Bryan, M Meehan, L Creevey, J Lynch… in British Journal of Cancer (2012)

Article

MicroRNA-204 increases sensitivity of neuroblastoma cells to cisplatin and is associated with a favourable clinical outcome

Neuroblastoma remains a major cause of cancer-linked mortality in children. miR-204 has been used in microRNA expression signatures predictive of neuroblastoma patient survival. The aim of this study was to ex...

J Ryan, A Tivnan, J Fay, K Bryan, M Meehan, L Creevey, J Lynch… in British Journal of Cancer (2012)

Article

Angiotensin-converting enzyme gene variants are associated with both cortisol secretion and late-life depression

Angiotensin-converting enzyme (ACE) is assumed to influence the activity of the hypothalamic–pituitary–adrenocortical (HPA) axis, which shows hyperactivity in depressed patients. ACE could thus be a promising can...

M-L Ancelin, I Carrière, J Scali, K Ritchie, I Chaudieu, J Ryan in Translational Psychiatry (2013)

Article

Bcl-xL controls a switch between cell death modes during mitotic arrest

Antimitotic agents such as microtubule inhibitors (paclitaxel) are widely used in cancer therapy while new agents blocking mitosis onset are currently in development. All these agents impose a prolonged mitoti...

N Bah, L Maillet, J Ryan, S Dubreil, F Gautier, A Letai, P Juin… in Cell Death & Disease (2014)

Article

Erratum: Bcl-xL controls a switch between cell death modes during mitotic arrest

Correction to: Cell Death and Disease (2014) 5, e1291; doi:10.1038/cddis.2014.251; published online 12 June 2014 Since the publication of this article the authors have noticed an error in Figure 7c. pS62DBcl-x...

N Bah, L Maillet, J Ryan, S Dubreil, F Gautier, A Letai, P Juin… in Cell Death & Disease (2014)

Article

C-reactive protein gene variants: independent association with late-life depression and circulating protein levels

C-reactive protein (CRP) is a heritable biomarker of systemic inflammation that is commonly elevated in depressed patients. Variants in the CRP gene that influence protein levels could thus be associated with dep...

M-L Ancelin, A Farré, I Carrière, K Ritchie, I Chaudieu, J Ryan in Translational Psychiatry (2015)

Article

BDNF promoter methylation and genetic variation in late-life depression

The regulation of the brain-derived neurotrophic factor (BDNF) is important for depression pathophysiology and epigenetic regulation of the BDNF gene may be involved. This study investigated whether BDNF methylat...

V Januar, M-L Ancelin, K Ritchie, R Saffery, J Ryan in Translational Psychiatry (2015)

Article

International experience of pregnancy outcomes in auto-inflammatory syndromes treated with Interleukin-1 inhibitors

T Youngstein, P Hoffmann, T Lane, R Williams, D Rowczenio… in Pediatric Rheumatology (2015)

Article

The effects of maternal anxiety during pregnancy on IGF2/H19 methylation in cord blood

Compelling evidence suggests that maternal mental health in pregnancy can influence fetal development. The imprinted genes, insulin-like growth factor 2 (IGF2) and H19, are involved in fetal growth and each is re...

T Mansell, B Novakovic, B Meyer, P Rzehak, P Vuillermin… in Translational Psychiatry (2016)

Article

36th International Symposium on Intensive Care and Emergency Medicine

P001 - Sepsis impairs the capillary response within hypoxic capillaries and decreases erythrocyte oxygen-dependent ATP efflux

R. M. Bateman, M. D. Sharpe, J. E. Jagger, C. G. Ellis, J. Solé-Violán… in Critical Care (2016)

Article

Erratum to: 36th International Symposium on Intensive Care and Emergency Medicine

Author et al, R. M. Bateman, M. D. Sharpe, J. E. Jagger, C. G. Ellis… in Critical Care (2016)

Article

Preliminary indications of the effect of a brief yoga intervention on markers of inflammation and DNA methylation in chronically stressed women

Yoga is associated with reduced stress and increased well-being, although the molecular basis for these benefits is not clear. Mounting evidence implicates the immune response, with current studies focused on ...

K N Harkess, J Ryan, P H Delfabbro, S Cohen-Woods in Translational Psychiatry (2016)

Article

5-HTTLPR × stress hypothesis: is the debate over?

M-L Ancelin, J Ryan in Molecular Psychiatry (2018)

Article

Erratum to: The Association Between Frailty and All-Cause Mortality in Community-Dwelling Older Individuals: An Umbrella Review

A. R. M. Saifuddin Ekram, R. L. Woods, C. Britt… in The Journal of Frailty & Aging (2022)

Article

Estrogen-related receptor gamma regulates mitochondrial and synaptic genes and modulates vulnerability to synucleinopathy

Many studies implicate mitochondrial dysfunction as a key contributor to cell loss in Parkinson disease (PD). Previous analyses of dopaminergic (DAergic) neurons from patients with Lewy-body pathology revealed...

S. N. Fox, L. J. McMeekin, C. H. Savage, K. L. Joyce, S. M. Boas… in npj Parkinson's Disease (2022)

Article

Correlates of Meal Skip** in Community Dwelling Older Adults: A Cross-Sectional Study

In this cross-sectional analysis of 10,071 community dwelling adults aged ≥70 years, we examined factors associated with meal skip** (self-reported) using multivariable logistic regression. Prevalence of mea...

H. Wild, D. Gasevic, R. L. Woods, J. Ryan… in The journal of nutrition, health & aging (2023)