6 Result(s)

Article

Angiotensin-converting enzyme gene variants are associated with both cortisol secretion and late-life depression

Angiotensin-converting enzyme (ACE) is assumed to influence the activity of the hypothalamic–pituitary–adrenocortical (HPA) axis, which shows hyperactivity in depressed patients. ACE could thus be a promising can...

M-L Ancelin, I Carrière, J Scali, K Ritchie, I Chaudieu, J Ryan in Translational Psychiatry (2013)

Article

C-reactive protein gene variants: independent association with late-life depression and circulating protein levels

C-reactive protein (CRP) is a heritable biomarker of systemic inflammation that is commonly elevated in depressed patients. Variants in the CRP gene that influence protein levels could thus be associated with dep...

M-L Ancelin, A Farré, I Carrière, K Ritchie, I Chaudieu, J Ryan in Translational Psychiatry (2015)

Article

BDNF promoter methylation and genetic variation in late-life depression

The regulation of the brain-derived neurotrophic factor (BDNF) is important for depression pathophysiology and epigenetic regulation of the BDNF gene may be involved. This study investigated whether BDNF methylat...

V Januar, M-L Ancelin, K Ritchie, R Saffery, J Ryan in Translational Psychiatry (2015)

Article

The effects of maternal anxiety during pregnancy on IGF2/H19 methylation in cord blood

Compelling evidence suggests that maternal mental health in pregnancy can influence fetal development. The imprinted genes, insulin-like growth factor 2 (IGF2) and H19, are involved in fetal growth and each is re...

T Mansell, B Novakovic, B Meyer, P Rzehak, P Vuillermin… in Translational Psychiatry (2016)

Article

Preliminary indications of the effect of a brief yoga intervention on markers of inflammation and DNA methylation in chronically stressed women

Yoga is associated with reduced stress and increased well-being, although the molecular basis for these benefits is not clear. Mounting evidence implicates the immune response, with current studies focused on ...

K N Harkess, J Ryan, P H Delfabbro, S Cohen-Woods in Translational Psychiatry (2016)

Article

5-HTTLPR × stress hypothesis: is the debate over?

M-L Ancelin, J Ryan in Molecular Psychiatry (2018)